Synthesis and Antibacterial Screening of Novel Fluorine Containing Heterocycles

被引：8
作者：
Karale, B. K. [1 ]
Takate, S. J. [2 ]
Salve, S. P. [2 ]
Zaware, B. H. [2 ]
Jadhav, S. S. [2 ]
机构：
[1] Radhabai Kale Mahila Mahavidyalya, Dept Chem, Ahmednagar 414001, India
[2] New Arts Commerce & Sci Coll, Dept Chem, Ahmednagar 414001, India
来源：
ORIENTAL JOURNAL OF CHEMISTRY | 2015年 / 31卷 / 01期
关键词：
Aurones; Flavonoids; Fluorine; Pyrazoles; Pyrazolines;
D O I：
10.13005/ojc/310135
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A Claisen-Schimidt condensation of 2-hydroxyacetophenones 1a-f with an aldehyde 2 yielded a series of compounds 3a-f. Compounds 3a-f were transformed into series of substituted chromones 4a-f, pyrazolines 5a-f and aurones 6a-f on treatment with DMSO/ I-2 NH2NH2/ EtOH and Hg(OAc)(2) / pyridine respectively. All these novel compounds were characterized by spectral techniques. All the compounds were screened for their antibacterial potential.
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收藏
页码：307 / 315
页数：9
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