Synthesis and Charactersation of Biodegradable Polyesteramide Based on poly (epsilon-caprolactone) and Study of Degradation

Poly (e-caprolactone) macromonomers carrying amide end groups were synthesed via a polycondensation reaction of functional carboxylic diacid terminated poly(epsilon-caprolactone) prepolymers (HOOC-PCL-COOH) with 1,4 phenylene bis(2-Oxazoline). The prepolymers were produced by the ring opening polymersation of epsilon-caprolactone by adipic acidic. This polymersation used a new one-step method that eliminated the need to isolate of the telechelic prepolymer intermediate. The expected structures of the polymers were confirmed by FTIR. Hydrolytic and enzymatic degradations of the materials were performed.