PERCUTANEOUS-ABSORPTION OF ZINC FROM ZINC-OXIDE APPLIED TOPICALLY TO INTACT SKIN IN MAN

被引：50

作者：

AGREN, MS

机构：

[1] Department of Pathology, Faculty of Health Sciences

来源：

DERMATOLOGICA | 1990年 / 180卷 / 01期

关键词：

human skin; suction blisters; Zinc penetration;

D O I：

10.1159/000247982

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The penetration of zinc through normal skin treated with a zinc oxide (25%) medicated occlusive dressing was studied. The mean release rate of zinc to the skin was 5 μg/cm2/h. After 48 h of treatment suction blisters were raised by the 'Kiistala' method. The zinc concentration of the epidermis, blister fluid and dermis was increased beneath the zinc dressing compared to control-treated skin. The study shows that zinc permeates intact human skin from topically applied zinc oxide in vivo.

引用

页码：36 / 39

页数：4

共 9 条

[1] A STUDY OF THE PERCUTANEOUS-ABSORPTION FROM TOPICALLY APPLIED ZINC-OXIDE OINTMENT [J].