MARKED INCREASES IN PLASMA-CATECHOLAMINE CONCENTRATIONS PRECEDE HYPOTENSION AND BRADYCARDIA CAUSED BY 8-HYDROXY-2-(DI-N-PROPYLAMINO) TETRALIN (8-OH-DPAT) IN CONSCIOUS RATS

被引：36
作者：
BAGDY, G [1 ]
SZEMEREDI, K [1 ]
MURPHY, DL [1 ]
机构：
[1] NINCDS,CLIN NEUROSCI BRANCH,BETHESDA,MD 20205
来源：
JOURNAL OF PHARMACY AND PHARMACOLOGY | 1989年 / 41卷 / 04期
关键词：
D O I：
10.1111/j.2042-7158.1989.tb06450.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：270 / 272
页数：3
相关论文
共 15 条
[1]   FOOD-INTAKE, NEURO-ENDOCRINE AND TEMPERATURE EFFECTS OF 8-OHDPAT IN THE RAT [J].
AULAKH, CS ;
WOZNIAK, KM ;
HAAS, M ;
HILL, JL ;
ZOHAR, J ;
MURPHY, DL .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 146 (2-3) :253-259
[2]   EVIDENCE THAT 8-HYDROXY-2-(N-DIPROPYLAMINO)TETRALIN (8-OH-DPAT) IS A SELECTIVE ALPHA-2-ADRENOCEPTOR ANTAGONIST ON GUINEA-PIG SUBMUCOUS NEURONS [J].
CRIST, J ;
SURPRENANT, A .
BRITISH JOURNAL OF PHARMACOLOGY, 1987, 92 (02) :341-347
[3]  
EISENHOFER G, 1986, CLIN CHEM, V32, P2030
[4]   CARDIOVASCULAR-RESPONSE TO 8-HYDROXY-2-(DI-N-PROPYLAMINO) TETRALIN (8-OH-DPAT) IN THE RAT - SITE OF ACTION AND PHARMACOLOGICAL ANALYSIS [J].
FOZARD, JR ;
MIR, AK ;
MIDDLEMISS, DN .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1987, 9 (03) :328-347
[5]   ACUTE ADMINISTRATION OF 8-HYDROXY-2-(DI-N-PROPYL-AMINO)TETRALIN (8-OH-DPAT), A SELECTIVE 5-HT-RECEPTOR AGONIST, CAUSES A BIPHASIC BLOOD-PRESSURE RESPONSE AND A BRADYCARDIA IN THE NORMOTENSIVE SPRAGUE-DAWLEY RAT AND IN THE SPONTANEOUSLY HYPERTENSIVE RAT [J].
GRADIN, K ;
PETTERSSON, A ;
HEDNER, T ;
PERSSON, B .
JOURNAL OF NEURAL TRANSMISSION, 1985, 62 (3-4) :305-319
[6]   PHARMACOLOGICAL EVIDENCE FOR A FUNCTIONAL-ROLE OF THE PREJUNCTIONAL ALPHA-ADRENORECEPTOR IN NORADRENERGIC NEUROTRANSMISSION IN THE CONSCIOUS RAT [J].
GRAHAM, RM ;
STEPHENSON, WH ;
PETTINGER, WA .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1980, 311 (02) :129-138
[7]   BIOCHEMICAL-CHARACTERIZATION OF ENKEPHALIN-LIKE IMMUNOREACTIVE PEPTIDES OF ADRENAL-GLANDS [J].
HEXUM, TD ;
YANG, HYT ;
COSTA, E .
LIFE SCIENCES, 1980, 27 (13) :1211-1216
[8]   8-HYDROXY-2-(DI-NORMAL-PROPYLAMINO)TETRALIN, 8-OH-DPAT, A POTENT AND SELECTIVE SIMPLIFIED ERGOT CONGENER WITH CENTRAL 5-HT-RECEPTOR STIMULATING ACTIVITY [J].
HJORTH, S ;
CARLSSON, A ;
LINDBERG, P ;
SANCHEZ, D ;
WIKSTROM, H ;
ARVIDSSON, LE ;
HACKSELL, U ;
NILSSON, JLG .
JOURNAL OF NEURAL TRANSMISSION, 1982, 55 (03) :169-188
[9]  
MARTIN GE, 1985, ARCH INT PHARMACOD T, V273, P251
[10]  
MCCALL RB, 1987, J PHARMACOL EXP THER, V242, P1152
12