SUSCEPTIBILITY OF ENCEPHALITOZOON-CUNICULI TO SEVERAL DRUGS IN-VITRO

被引：45

作者：

FRANSSEN, FFJ

LUMEIJ, JT

VANKNAPEN, F

机构：

[1] UNIV UTRECHT,FAC VET MED,DEPT CLIN SCI COMPAN ANIM,AVIAN & EXOT ANIM MED SECT,3508 TD UTRECHT,NETHERLANDS

[2] NATL INST PUBL HLTH & ENVIRONM PROTECT,PARASITOL & MYCOL LAB,3720 BA BILTHOVEN,NETHERLANDS

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 06期

关键词：

D O I：

10.1128/AAC.39.6.1265

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In the light of the increased incidence of human Encephalitozoon infections and the absence of an established treatment protocol, a simple in vitro testing method to compare activities of drugs against Encephalitozoon cuniculi was developed. With this in vitro method, the 50% inhibitory concentrations of fumagillin, thiabendazole, albendazole, oxibendazole, and propamidine isethionate for E. cuniculi in rabbit kidney cells were determined. Itraconazole, toltrazuril, metronidazole, ronidazole, and ganciclovir were ineffective in this testing system.

引用

页码：1265 / 1268

页数：4

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