INFLUENCE OF TENIPOSIDE ON PLATELET FUNCTIONS IN-VITRO

被引：6

作者：

KUBISZ, P

SEGHIER, F

DOBROTORA, M

STASKO, J

CRONBERG, S

机构：

[1] MALMO GEN HOSP,DEPT INFECT DIS,S-21401 MALMO,SWEDEN

[2] UNIV HOSP MARTIN,DIV HEMATOL,MARTIN,SLOVAKIA

[3] UNIV HOSP ORAN,DIV HEMOBIOL,ORAN,ALGERIA

来源：

THROMBOSIS RESEARCH | 1995年 / 77卷 / 02期

关键词：

CYTOTOXIC DRUGS; TENIPOSIDE; PLATELET FUNCTIONS; TUMOR CHEMOTHERAPY;

D O I：

10.1016/0049-3848(95)91620-Z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Teniposide added to citrated platelet-rich plasma reduced platelet aggregation induced by collagen, but did not interfere with ADP-induced aggregation. The availability of platelet factor 3 was decreased irrespective of inducer. Reptilase clot retraction induced by ADP or collagen was reduced. Teniposide did not interfere with platelet adhesion to glass. It did not release lactic dehydrogenase from the cytoplasm of platelets. Coagulation factors were not affected.

引用

页码：145 / 148

页数：4