RECURRENCE OF PRIMARY BILIARY-CIRRHOSIS AFTER LIVER-TRANSPLANTATION FOLLOWING FK506-BASED IMMUNOSUPPRESSION

被引：58

作者：

WONG, PYN

PORTMANN, B

OGRADY, JG

DEVLIN, JJ

HEGARTY, JE

TAN, KC

WILLIAMS, R

机构：

[1] KINGS COLL HOSP & SCH MED & DENT,INST LIVER STUDIES,LONDON SE5 8RS,ENGLAND

[2] ST VINCENTS HOSP,DUBLIN 4,IRELAND

来源：

JOURNAL OF HEPATOLOGY | 1993年 / 17卷 / 03期

关键词：

PRIMARY BILIARY CIRRHOSIS; ORTHOTOPIC LIVER TRANSPLANTATION; GRAFT DYSFUNCTION; CHOLESTASIS; LIVER BIOPSY;

D O I：

10.1016/S0168-8278(05)80206-5

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report two cases of recurrence of primary biliary cirrhosis (PBC) in the transplanted liver whilst maintained on a FK506-based immunosuppressive regime, the first to be described. One patient experienced symptoms in association with the development of cholestasis. In both there was a persistence of serological markers of PBC and liver histology revealed florid bile duct destruction and a granulomatous reaction.

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页码：284 / 287

页数：4

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