LYMPHOCYTE SUB-POPULATIONS IN LYMPHOPROLIFERATIVE DISEASES - PARALLEL TUBULAR STRUCTURES IN FC RECEPTOR-BEARING LYMPHOCYTES

被引:17
|
作者
HALIE, MR [1 ]
BLOM, N [1 ]
KLOOSTERMAN, T [1 ]
SMIT, JW [1 ]
机构
[1] STATE UNIV GRONINGEN, DEPT MED, DIV HAEMATOL, GRONINGEN, NETHERLANDS
关键词
Fc receptors; Hodgkin lymphocytes; Parallel tubular structures;
D O I
10.1159/000207532
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In analogy with the data of Henkart and Henkart for normal persons, lymphocytes with parallel tubular structures (PTS or the macrotubular bundle) of patients with Hodgkin’s disease were all found to bear an Fc receptor on their cell membrane (EA-RFC). An explanation for this correlation of EA-RFC and PTS or for the increase of EA-RFC in some patients with Hodgkin’s disease was not yet found. Comparison of groups of 22 normal subjects, 20 patients with Hodgkin's disease, 20 with chronic lymphatic leukemia, and 20 with non-Hodgkin lymphoma showed the EA-RFC to be increased in the Hodgkin group. They were decreased in CLL patients, while mouse erythrocyte rosette-forming cells and membrane surface immunoglobulins in this group were increased. Surface Ig and EA-RFC varied widely in the non-Hodgkin lymphoma group of patients. © 1979 S. Karger AG, Basel.
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页码:25 / 31
页数:7
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