X-RAY CRYSTALLOGRAPHIC STUDY OF BINDING OF PEPTIDE CHLOROMETHYL KETONE INHIBITORS TO SUBTILISIN BPN'

被引：207
作者：
ROBERTUS, JD
POWERS, JC
WILCOX, PE
ALDEN, RA
BIRKTOFT, JJ
KRAUT, J
机构：
来源：
BIOCHEMISTRY | 1972年 / 11卷 / 13期
关键词：
D O I：
10.1021/bi00763a009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：2439 / &
相关论文
共 35 条
[1]   ATOMIC COORDINATES FOR SUBTILISIN BPN' (OR NOVO) [J].
ALDEN, RA ;
BIRKTOFT, JJ ;
KRAUT, J ;
ROBERTUS, JD ;
WRIGHT, CS .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1971, 45 (02) :337-&
[2]   A HYDROGEN-BOND NETWORK AT ACTIVE SITE OF SUBTILISIN BPN [J].
ALDEN, RA ;
WRIGHT, CS ;
KRAUT, J .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 1970, 257 (813) :119-&
[3]  
BIRKTOFT JJ, IN PRESS
[4]  
Blow D.M., 1971, The Enzymes, V3, P185, DOI DOI 10.1016/S1874-6047(08)60397-2
[5]   ROLE OF A BURIED ACID GROUP IN MECHANISM OF ACTION OF CHYMOTRYPSIN [J].
BLOW, DM ;
BIRKTOFT, JJ ;
HARTLEY, BS .
NATURE, 1969, 221 (5178) :337-&
[6]   CONCEPT OF ORBITAL STEERING IN CATALYTIC REACTIONS [J].
BRUICE, TC ;
BROWN, A ;
HARRIS, DO .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (03) :658-&
[7]  
DAFFORN GA, 1971, P NATL ACAD SCI USA, V68, P2463
[8]  
DAYHOFF MO, 1969, ATLAS PROTEIN SEQUEN, V4, P49
[9]   MECHANISM OF THE REACTION OF CHYMOTRYPSIN WITH PARA-NITROPHENYL ACETATE [J].
GUTFREUND, H ;
STURTEVANT, JM .
BIOCHEMICAL JOURNAL, 1956, 63 (04) :656-661
[10]  
HENDERSON R, 1970, Journal of Molecular Biology, V54, P341, DOI 10.1016/0022-2836(70)90434-1
1234