A LONGITUDINAL COMPARATIVE HISTOMETRIC STUDY OF THE BIOCOMPATIBILITY OF 3 LOCAL HEMOSTATIC AGENTS

被引：12

作者：

MATTSSON, T

ANDERSSEN, K

KOENDELL, PA

LINDSKOG, S

机构：

[1] KAROLINSKA INST,DEPT ORAL SURG,S-10401 STOCKHOLM 60,SWEDEN

[2] KAROLINSKA INST,DEPT HISTOL & NEUROBIOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1990年 / 19卷 / 01期

关键词：

biocompatibility; bone; hemostatic agents; histomorphometry;

D O I：

10.1016/S0901-5027(05)80568-5

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The biocompatibility was studied of 3 hemostatic agents (Astroplast™), Hemastogen™ and bone wax) implanted into experimental bone cavities together with their clearance from the implantation sites. The 3 agents had an acceptable hemostatic effect during the surgical procedure. However, marked differences regarding tissue reactions in the experimental bone cavities, as well as at the internal bone surfaces, were found between them. Astroplast and Hemastogen appear to provoke more adverse tissue reactions, including foreign body giant cell formation, compared with bone wax. All 3 hemostatic implants showed markedly delayed bone healing. It was concluded that their biocompatibility was not ideal but acceptable in view of the clinical advantages. © 1990 Munksgaard International Publishers Ltd.

引用

页码：47 / 50

页数：4

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