DIRECT ENANTIOMERIC SEPARATION OF BETAXOLOL WITH APPLICATIONS TO ANALYSIS OF BULK DRUG AND BIOLOGICAL SAMPLES

被引：60
作者：
KRSTULOVIC, AM [1 ]
FOUCHET, MH [1 ]
BURKE, JT [1 ]
GILLET, G [1 ]
DURAND, A [1 ]
机构：
[1] LAB ETUD & RECH SYNTHELABO,PHARMACOCINET & METAB,F-92366 MEUDON LA FORET,FRANCE
来源：
JOURNAL OF CHROMATOGRAPHY | 1988年 / 452卷
关键词：
D O I：
10.1016/S0021-9673(01)81470-9
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
引用
收藏
页码：477 / 483
页数：7
相关论文
共 10 条
[1]   DETERMINATION OF BETAXOLOL ENANTIOMERS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - APPLICATION TO PHARMACOKINETIC STUDIES [J].
DARMON, A ;
THENOT, JP .
JOURNAL OF CHROMATOGRAPHY, 1986, 374 (02) :321-328
[2]   CHARACTERIZATION OF A COMMON GENETIC-DEFECT OF CYTOCHROME-P-450 FUNCTION (DEBRISOQUINE-SPARTEINE TYPE POLYMORPHISM) - INCREASED MICHAELIS CONSTANT (KM) AND LOSS OF STEREOSELECTIVITY OF BUFURALOL 1'-HYDROXYLATION IN POOR METABOLIZERS [J].
DAYER, P ;
GASSER, R ;
GUT, J ;
KRONBACH, T ;
ROBERTZ, GM ;
EICHELBAUM, M ;
MEYER, UA .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 125 (01) :374-380
[3]   STERIC CONFIGURATION AND POLYMORPHIC OXIDATION OF LIPOPHILIC BETA-ADRENOCEPTOR BLOCKING-AGENTS - INVIVO INVITRO CORRELATIONS [J].
DAYER, P ;
LEEMANN, T ;
GUT, J ;
KRONBACH, T ;
KUPFER, A ;
FRANCIS, R ;
MEYER, UA .
BIOCHEMICAL PHARMACOLOGY, 1985, 34 (03) :399-400
[4]  
GUILLOUZO A, 1986, HEPATOCYTES ISOLES C
[5]   DETERMINATION OF (R)-ALPRENOLOL AND (S)-ALPRENOLOL AND (R)-METOPROLOL AND (S)-METOPROLOL AS THEIR DIASTEREOMERIC DERIVATIVES IN HUMAN-PLASMA BY REVERSED-PHASE LIQUID-CHROMATOGRAPHY [J].
HERMANSSON, J ;
VONBAHR, C .
JOURNAL OF CHROMATOGRAPHY, 1982, 227 (01) :113-127
[6]  
KRSTULOVIC AM, IN PRESS J PHARM BIO
[7]   CHROMATOGRAPHIC RESOLUTION .12. OPTICAL RESOLUTION OF BETA-BLOCKERS BY HPLC ON CELLULOSE TRIPHENYLCARBAMATE DERIVATIVES [J].
OKAMOTO, Y ;
KAWASHIMA, M ;
ABURATANI, R ;
HATADA, K ;
NISHIYAMA, T ;
MASUDA, M .
CHEMISTRY LETTERS, 1986, (07) :1237-1240
[8]   PROPOSAL FOR THE CLASSIFICATION OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC CHIRAL STATIONARY PHASES - HOW TO CHOOSE THE RIGHT COLUMN [J].
WAINER, IW .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1987, 6 (05) :125-134
[9]   STEREOSELECTIVE RING OXIDATION OF PROPRANOLOL IN MAN [J].
WALLE, T ;
WALLE, UK ;
WILSON, MJ ;
FAGAN, TC ;
GAFFNEY, TE .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 18 (05) :741-747
[10]   BLOOD-CONCENTRATIONS AND PHARMACODYNAMIC EFFECTS OF BETAXOLOL (SL 75212) A NEW BETA-ADRENOCEPTOR ANTAGONIST AFTER ORAL AND INTRAVENOUS ADMINISTRATION [J].
WARRINGTON, SJ ;
TURNER, P ;
KILBORN, JR ;
BIANCHETTI, G ;
MORSELLI, PL .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 10 (05) :449-452
1