Synthesis and in Vitro Antimicrobial Evaluation of Benzothiazole Incorporated Thiazolidin-4-ones Derivatives

被引：16

作者：

Agarwal, Shikha ^{[1
]}

Agarwal, Dinesh Kumar ^{[2
]}

Gautam, Naveen ^{[3
]}

Agarwal, Kshamta ^{[4
]}

Gautam, Dinesh Chandra ^{[4
]}

机构：

[1] Mohan Lal Sukhadia Univ, Dept Chem, Udaipur 313001, India

[2] Arya Coll Pharm, Dept Pharmacol, Jaipur 303101, Rajasthan, India

[3] LBS Govt PG Coll, Dept Chem, Jaipur 303108, Rajasthan, India

[4] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

JOURNAL OF THE KOREAN CHEMICAL SOCIETY-DAEHAN HWAHAK HOE JEE | 2014年 / 58卷 / 01期

关键词：

Benzothiazole; Thiazolidin-4-ones; N-(5,7-dimethylbenzo[d]thiazol-2-yl)hydrazine carboxamide; Antimicrobial activity;

D O I：

10.5012/jkcs.2014.58.1.33

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the course of work on new pharmacologically active antimicrobial agents, we have reported the synthesis of a new class of structurally novel derivatives, incorporating two bioactive structures, a benzothiazole and thiazolidin-4-one, to yield a class of compounds having interesting antimicrobial properties. The antimicrobial properties of the synthesized compounds were investigated against bacteria (Staphylococcus aureus and Escherchia coli) and fungi (Candida albicans and Aspergillus niger) using serial plate dilution method. The structure of the synthesized compounds have been established by elemental analysis and spectroscopic data.

引用

页码：33 / 38

页数：6

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