PROKARYOTIC HU AND EUKARYOTIC HMG1 - A KINKED RELATIONSHIP

被引：65
作者：
BIANCHI, ME [1 ]
机构：
[1] DIBIT,IST SCI SAN RAFFAELE,I-20132 MILAN,ITALY
来源：
MOLECULAR MICROBIOLOGY | 1994年 / 14卷 / 01期
关键词：
D O I：
10.1111/j.1365-2958.1994.tb01261.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
HU and IHF proteins have long been considered the prokaryotic analogues of eukaryotic histones. Their ability to bend DNA, however, is distinctly similar to that of eukaryotic HMG-box proteins, a recently identified family of chromatin components and transcription factors. In some conditions, HU and HMG1-like proteins can even be swapped, both in vitro and in vivo. In spite of this, HU/IHF and HMG-box proteins are not evolutionarily related, and represent two independent solutions for the same biochemical problem.
引用
收藏
页码：1 / 5
页数：5
相关论文
共 33 条
[1]   SHORT-RANGE DNA LOOPING BY THE XENOPUS HMG-BOX TRANSCRIPTION FACTOR, XUBF [J].
BAZETTJONES, DP ;
LEBLANC, B ;
HERFORT, M ;
MOSS, T .
SCIENCE, 1994, 264 (5162) :1134-1137
[2]   SPECIFIC RECOGNITION OF CRUCIFORM DNA BY NUCLEAR-PROTEIN HMG1 [J].
BIANCHI, ME ;
BELTRAME, M ;
PAONESSA, G .
SCIENCE, 1989, 243 (4894) :1056-1059
[3]  
BIANCHI ME, 1992, NUCLEIC ACIDS MOL BI, V6, P112
[4]  
BIANCHI ME, 1994, MANIPULATION DNA STR
[5]   HU, THE MAJOR HISTONE-LIKE PROTEIN OF ESCHERICHIA-COLI, MODULATES THE BINDING OF IHF TO ORIC [J].
BONNEFOY, E ;
ROUVIEREYANIV, J .
EMBO JOURNAL, 1992, 11 (12) :4489-4496
[6]   HISTONE-LIKE PROTEINS OF BACTERIA [J].
DRLICA, K ;
ROUVIEREYANIV, J .
MICROBIOLOGICAL REVIEWS, 1987, 51 (03) :301-319
[7]   DNA DYNAMIC FLEXIBILITY AND PROTEIN RECOGNITION - DIFFERENTIAL STIMULATION BY BACTERIAL HISTONE-LIKE PROTEIN HU [J].
FLASHNER, Y ;
GRALLA, JD .
CELL, 1988, 54 (05) :713-721
[8]   THE ROLE OF INTEGRATION HOST FACTOR IN GENE-EXPRESSION IN ESCHERICHIA-COLI [J].
FREUNDLICH, M ;
RAMANI, N ;
MATHEW, E ;
SIRKO, A ;
TSUI, P .
MOLECULAR MICROBIOLOGY, 1992, 6 (18) :2557-2563
[9]   THE HMG DOMAIN OF LYMPHOID ENHANCER FACTOR-I BENDS DNA AND FACILITATES ASSEMBLY OF FUNCTIONAL NUCLEOPROTEIN STRUCTURES [J].
GIESE, K ;
COX, J ;
GROSSCHEDL, R .
CELL, 1992, 69 (01) :185-195
[10]   HMG DOMAIN PROTEINS - ARCHITECTURAL ELEMENTS IN THE ASSEMBLY OF NUCLEOPROTEIN STRUCTURES [J].
GROSSCHEDL, R ;
GIESE, K ;
PAGEL, J .
TRENDS IN GENETICS, 1994, 10 (03) :94-100
1234