Splenic Marginal Zone Lymphoma in the Setting of Noncirrhotic Portal Hypertension

被引:1
作者
Ratnayake, Saman [1 ]
Ammar, Ali [1 ]
Rezvani, Rodd [1 ]
Petersen, Greti [1 ]
机构
[1] Kern Med Ctr, 1700 Mt Vernon Ave, Bakersfield, CA 93306 USA
来源
JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS | 2015年 / 3卷 / 04期
关键词
splenic marginal zone lymphoma; noncirrhotic portal hypertension; disseminated coccidioidomycosis;
D O I
10.1177/2324709615609385
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present a case of a 65-year-old Hispanic man with a history of disseminated cutaneous coccidioidomycosis who presented to the emergency room for progressively worsening abdominal pain associated with shortness of breath. The patient was found to have pleural effusion and moderate ascites on physical examination. Abdominal ultrasound and computed tomography scan were consistent with moderate ascites and portal hypertension but negative for both liver cirrhosis and for venous or arterial thrombosis. Cytology of ascitic fluid was suggestive of portal hypertension and was negative for infection. Subsequent, thoracentesis was suggestive of exudative effusion and also negative for infection. Liver biopsy confirmed the absence of cirrhosis. Complete blood count indicated pancytopenia, whereas bone marrow biopsy and flow cytometry were suggestive of marginal zone lymphoma (MZL). Clinically, the patient's shortness of breath was resolved by thoracentesis and paracentesis; however, his abdominal pain persisted. A diagnosis of idiopathic noncirrhotic portal hypertension in the setting of splenic MZL was made. The patient was transferred to a higher level of care for splenectomy; however, he missed multiple appointments. Since discharge, the patient has been seen in the outpatient setting and states that he is controlling his disease with diet and exercise; however, he continues to complain of intermittent shortness of breath with exertion.
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页数:5
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