HUMAN HUMORAL IMMUNE-RESPONSES AGAINST TRICHINELLA-SPIRALIS

被引：12

作者：

ALCANTARA, P

CORREA, D

机构：

[1] Departamento de Inmunoparasitología, Institute Nacional de Diagnóstico y Referencia Epidemiológicos, 'Dr Manuel Martínez Baez', SSa. Prol. Carpio 470

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1993年 / 23卷 / 05期

关键词：

ANTIBODIES; ANTIGENS; EITB; IMMUNE RESPONSE; ELECTRO-IMMUNO-TRANSFER BLOT; NEMATODA; TRICHINELLA-SPIRALIS; TRICHINOSIS; TRICHINOSIS AND WESTERN BLOT;

D O I：

10.1016/0020-7519(93)90173-V

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The analysis of trichinellosis patients' sera was performed by Western blot against a crude extract of Trichinella spiralis. Eight distinctive bands from 38 to 104 kDa were present in most of the patients' sera as a striking homogeneous response. Some of these characteristic bands were found to be recognized by the serum of infected rodents and of an immunized rabbit in this work, and have also been reported to be recognized by monoclonal and polyclonal antibodies from T. spiralis infected or immunized rats, mice, swine or rabbits. Our data indicate that different animal species as well as humans recognize unique immunodominant epitopes of T. spiralis.

引用

页码：657 / 660

页数：4

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