Update on the use of steroids in rheumatoid arthritis

被引：0

作者：

Garcia-Magallon, Blanca ^{[1
]}

Silva-Fernandez, Lucia ^{[2
]}

Luis Andreu-Sanchez, Jose ^{[1
]}

机构：

[1] Hosp Univ Puerta Hierro Majadahonda Majadahonda, Serv Reumatol, Madrid, Spain

[2] Hosp Univ Guadalajara, Secc Reumatol, Guadalajara, Spain

来源：

REUMATOLOGIA CLINICA | 2013年 / 9卷 / 05期

关键词：

Rheumatoid arthritis; Corticosteroids; Disease-modifying anti-rheumatic drugs;

D O I：

10.1016/j.reumae.2013.01.015

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Corticosteroids are a mainstay in the therapy of rheumatoid arthritis (RA). In recent years, a number of high-quality controlled clinical trials have shown their effect as a disease-modifying anti-rheumatic drug (DMARD) and a favourable safety profile in recent-onset RA. Despite this, they are more frequently used as bridge therapy while other DMARDs initiate their action than as true disease-modifying agents. Low-dose corticosteroid use during the first two years of disease slows radiologic damage and reduces the need of biologic therapy aimed at reaching a state of clinical remission in recent-onset RA. Thus, their systematic use in this clinical scenario should be considered. (C) 2013 Elsevier Espana, S.L. All rights reserved.

引用

页码：297 / 302

页数：6

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