INVIVO INCORPORATION OF C-14 PHENYLALANINE INTO ASCIDIAN TUNICHROME

被引：11

作者：

HE, X

KUSTIN, K

PARRY, DL

ROBINSON, WE

RUBERTO, G

NAKANISHI, K

机构：

[1] BRANDEIS UNIV, DEPT CHEM, BOX 9110, WALTHAM, MA 02254 USA

[2] NO TERR UNIV, SCH CHEM & EARTH SCI, CASUARINA, NT 0811, AUSTRALIA

[3] NEW ENGLAND AQUARIUM, HAROLD E EDGERTON RES LAB, BOSTON, MA 02110 USA

[4] UNIV CATANIA, CNR, IST STUDIO SOSTANZE NAT, I-95023 CATANIA, ITALY

[5] COLUMBIA UNIV, DEPT CHEM, NEW YORK, NY 10027 USA

来源：

EXPERIENTIA | 1992年 / 48卷 / 04期

关键词：

TUNICHROME; PHENYLALANINE; ASCIDIAN; TUNICATES; BLOOD PIGMENTS;

D O I：

10.1007/BF01923431

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ascidia ceratodes exposed to C-14-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (less-than-or-equal-to 4-mu-Ci/mol tunichrome = 22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57-mu-Ci/mol tunichrome = 318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.

引用

页码：367 / 371

页数：5

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