NGS technology makes microhaplotype a potential forensic marker

被引：16

作者：

Wang, Hui ^{[2
]}

Zhu, Jing ^{[1
]}

Zhou, Nan ^{[3
,4
]}

Jiang, Youjing ^{[1
]}

Wang, Li ^{[1
]}

He, Wang ^{[1
]}

Peng, Duo ^{[1
]}

Su, Qin ^{[1
]}

Mao, Jiong ^{[2
]}

Chan, Dan ^{[2
]}

Liang, Weibo ^{[1
]}

Zhang, Lin ^{[1
]}

机构：

[1] Sichuan Univ, Dept Forens Genet, West China Sch Basic Sci & Forens Med, 3-17 Renmin South Rd, Chengdu 610041, Sichuan, Peoples R China

[2] Chengdu Publ Secur Bur, Inst Forens Sci, Dept Forens Genet, Chengdu 610081, Sichuan, Peoples R China

[3] Sichuan Univ, Coll Life Sci, Chengdu 610041, Sichuan, Peoples R China

[4] Sichuan Univ, Minister Educ, Bioresources Key Lab, Chengdu 610041, Sichuan, Peoples R China

来源：

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES | 2015年 / 5卷

基金：

中国国家自然科学基金;

关键词：

NGS; Microhaplotype; SNP;

D O I：

10.1016/j.fsigss.2015.09.093

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Next generation sequencing (NGS) makes it realizable to integrate a cluster of SNPs and form a new type of forensic marker microhaplotype. We got a microhaplotype locus containing 3 SNPs and within the expanse of 164 bp from data of Illumina Mi-Seq, whose information approaches to STR locus. A panel of microhaplotype loci is helpful for individual identification, kinship analyses, ancestry inference and mixture. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E233 / E234

页数：2

共 3 条

[1] Haplotype block: a new type of forensic DNA markers
Ge, Jianye
Budowle, Bruce
Planz, John V.
Chakraborty, Ranajit
[J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2010, 124 (05) : 353 - 361
[2] Current sequencing technology makes microhaplotypes a powerful new type of genetic marker for forensics
Kidd, Kenneth K.
Pakstis, Andrew J.
Speed, William C.
Lagace, Robert
Chang, Joseph
Wootton, Sharon
Haigh, Eva
Kidd, Judith R.
[J]. FORENSIC SCIENCE INTERNATIONAL-GENETICS, 2014, 12 : 215 - 224
[3] Mini-haplotypes as lineage informative SNPs and ancestry inference SNPs
Pakstis, Andrew J.
Fang, Rixun
Furtado, Manohar R.
Kidd, Judith R.
Kidd, Kenneth K.
[J]. EUROPEAN JOURNAL OF HUMAN GENETICS, 2012, 20 (11) : 1148 - 1154

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