ANTIGEN-SPECIFICITY OF GAMMA-DELTA LYMPHOCYTES-T

被引：55
|
作者：
BORN, WK
OBRIEN, RL
MODLIN, RL
机构：
[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MICROBIOL & IMMUNOL,LOS ANGELES,CA 90024
[2] UNIV COLORADO,HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,DENVER,CO 80262
[3] UNIV CALIF LOS ANGELES,SCH MED,DIV DERMATOL,LOS ANGELES,CA 90024
来源：
FASEB JOURNAL | 1991年 / 5卷 / 12期
关键词：
GAMMA-DELTA T-CELLS; INFECTION; SPECIFICITY; FUNCTION;
D O I：
10.1096/fasebj.5.12.1717333
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Gamma-delta-T cells represent a new lymphocyte subset without a definitive functional assignment. Although in many ways similar to alpha-beta-T lymphocytes, they are clearly distinguished by their expression of a different set of T cell receptor genes, a different distribution in normal tissues, and perhaps also different ligand specificities. Because gamma-delta-T cells appear to be involved in a variety of human diseases, the determination of their biological role has become an important challenge for immunologists and researchers in related areas.
引用
收藏
页码：2699 / 2705
页数：7
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