Apoptotic Programmed Cell Death in Cancer and The Modern Methods for Detection of Apoptotic Cells: A Mini Review

Apoptosis is a process of a programmed cell death in all mammalian cells. Gaining understanding into the modern methods for detection of apoptotic cells will let the development of therapeutic agents with the properties to induced apoptotic cells death in cancer therapy. In this context, modern methods for detection of apoptotic cells play an important role to characterize the dying cells. In the present review, we outline the modern methods that are based on morphological analysis, flow cytometry analysis, cell quantification and mitochondrial membrane potential (Delta psi m) for detection of apoptotic cells death. We also present the basic principle of apoptotic cells death and related latest information in this review.