THE MACROPHAGE

被引：171

作者：

GORDON, S ^{[1
]}

机构：

[1] UNIV OXFORD, SIR WILLIAM DUNN SCH PATHOL, S PARKS RD, OXFORD OX1 3RE, ENGLAND

来源：

BIOESSAYS | 1995年 / 17卷 / 11期

关键词：

D O I：

10.1002/bies.950171111

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied repertoire of plasma membrane and secretory molecules. Upon isolation from the body it continues to express special, as well as general, features of cellular organisation and function, which make it a delight to study in cell culture.

引用

页码：977 / 986

页数：10

共 30 条

[1] MACROPHAGE COMPLEMENT AND LECTIN-LIKE RECEPTORS BIND LEISHMANIA IN THE ABSENCE OF SERUM [J].

BLACKWELL, JM ;

EZEKOWITZ, RAB ;

ROBERTS, MB ;

CHANNON, JY ;

SIM, RB ;

GORDON, S .

JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 162 (01) :324-331

[2] MONOCLONAL-ANTIBODY TO MURINE PECAM-1 (CD31) BLOCKS ACUTE-INFLAMMATION IN-VIVO [J].

BOGEN, S ;

PAK, J ;

GARIFALLOU, M ;

DENG, XH ;

MULLER, WA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (03) :1059-1064

[3] MOUSE MACROPHAGE HEMAGGLUTININ (SHEEP ERYTHROCYTE RECEPTOR) WITH SPECIFICITY FOR SIALYLATED GLYCOCONJUGATES CHARACTERIZED BY A MONOCLONAL-ANTIBODY [J].

CROCKER, PR ;

GORDON, S .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (04) :1333-1346

[4] SIALOADHESIN, A MACROPHAGE SIALIC-ACID BINDING-RECEPTOR FOR HEMATOPOIETIC-CELLS WITH 17 IMMUNOGLOBULIN-LIKE DOMAINS [J].

CROCKER, PR ;

MUCKLOW, S ;

BOUCKSON, V ;

MCWILLIAM, A ;

WILLIS, AC ;

GORDON, S ;

MILON, G ;

KELM, S ;

BRADFIELD, P .

EMBO JOURNAL, 1994, 13 (19) :4490-4503

[5]

EDIDIN M, 1994, LEGACY CELL FUSION, P101

[6] DIVALENT CATION-INDEPENDENT MACROPHAGE ADHESION INHIBITED BY MONOCLONAL-ANTIBODY TO MURINE SCAVENGER RECEPTOR [J].

FRASER, I ;

HUGHES, D ;

GORDON, S .

NATURE, 1993, 364 (6435) :343-345

[7] INVITRO SYNTHESIS AND SECRETION OF LYSOZYME BY MONONUCLEAR PHAGOCYTES [J].

GORDON, S ;

TODD, J ;

COHN, ZA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1974, 139 (05) :1228-1248

[8] MACROPHAGE-MELANOCYTE HETEROKARYONS .1. PREPARATION AND PROPERTIES [J].

GORDON, S ;

COHN, Z .

JOURNAL OF EXPERIMENTAL MEDICINE, 1970, 131 (05) :981-+

[9] PREPARATION AND PROPERTIES OF MACROPHAGE-L CELL HYBRIDS [J].

GORDON, S ;

RIPPS, CS ;

COHN, Z .

JOURNAL OF EXPERIMENTAL MEDICINE, 1971, 134 (05) :1187-&

[10] MACROPHAGE-MELANOCYTE HETEROKARYONS .2. ACTIVATION OF MACROPHAGE DNA SYNTHESIS - STUDIES WITH INHIBITORS OF RNA SYNTHESIS [J].

GORDON, S ;

COHN, Z .

JOURNAL OF EXPERIMENTAL MEDICINE, 1971, 133 (02) :321-+

← 1 2 3 →