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- [41] Preclinical Evaluation of Local JAK1 and JAK2 Inhibition in Cutaneous InflammationJOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 (09) : 1838 - 1844Fridman, Jordan S.Scherle, Peggy A.Collins, RobertBurn, TimothyNeilan, Claire L.Hertel, DeniseContel, NancyHaley, PatrickThomas, BethShi, JackCollier, PaulRodgers, James D.Shepard, StaceyMetcalf, BrianHollis, GregoryNewton, Robert C.Yeleswaram, SwamyFriedman, Steven M.Vaddi, Kris
- [42] Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246Labadie, Sharada S.
- [43] Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancersCLINICAL CANCER RESEARCH, 2008, 14 (12) : 3716 - 3721Jeong, Eun GooKim, Min SungNam, Hyo KyungMin, Chang KiLee, SeokChung, Yeun JunYoo, Nam JinLee, Sug Hyung
- [44] An indel polymorphism in the 3′ untranslated region of JAK1 confers risk for hepatocellular carcinoma possibly by regulating JAK1 transcriptional activity in a Chinese populationONCOLOGY LETTERS, 2018, 15 (05) : 8088 - 8094Yu, QiangQian, WeifengWang, JianWu, YejiaoZhang, JinkunChen, Weichang
- [45] Atomic Simulation of the Binding of JAK1 and JAK2 with the Selective Inhibitor RuxolitinibINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (18)Kondratyev, MaximRudnev, Vladimir R.Nikolsky, Kirill S.Stepanov, Alexander A.Petrovsky, Denis, VKulikova, Liudmila, IKopylov, Arthur T.Malsagova, Kristina A.Kaysheva, Anna L.
- [46] Generation of Janus kinase 1 (JAK1) conditional knockout miceGENESIS, 2016, 54 (11) : 582 - 588Sakamoto, KazuhitoWehde, Barbara L.Raedler, Patrick D.Triplett, Aleata A.Wagner, Kay-Uwe
- [47] Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (24) : 7627 - 7633Labadie, SharadaDragovich, Peter S.Barrett, KathyBlair, Wade S.Bergeron, PhilippeChang, ChristineDeshmukh, GauriEigenbrot, CharlesGhilardi, NicoGibbons, PaulHurley, Christopher A.Johnson, AdamKenny, Jane R.Kohli, Pawan BirKulagowski, Janusz J.Liimatta, MaryaLupardus, Patrick J.Mendonca, RohanMurray, Jeremy M.Pulk, RebeccaShia, StevenSteffek, MicahUbhayakar, SavitaUltsch, Markvan Abbema, AnneWard, StuartZak, Mark
- [48] Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infectionNature Communications, 7Davide ElettoSiobhan O. BurnsIvan AnguloVincent PlagnolKimberly C. GilmourFrances HenriquezJames CurtisMiguel GasparKarolin NowakVanessa Daza-CajigalDinakantha KumararatneRainer DoffingerAdrian J. ThrasherSergey Nejentsev
- [49] Selective JAK1 inhibitors for the treatment of inflammatory bowel diseasePHARMACOLOGY & THERAPEUTICS, 2023, 245Nielsen, Ole HaagenBoye, Theresa LouiseGubatan, JohnChakravarti, DeepavaliJaquith, James B.LaCasse, Eric C.
- [50] Multispecies-targeting siRNAs for the modulation of JAK1 in the skinMOLECULAR THERAPY NUCLEIC ACIDS, 2024, 35 (01):Tang, QiGross, Katherine Y.Fakih, Hassan H.Jackson, Samuel O.Abideen, Mohammad Zain U. I.Monopoli, Kathryn R.Blanchard, CarineBouix-Peter, ClairePortal, ThibaudHarris, John E.Khvorova, AnastasiaAlterman, Julia F.