共 50 条
- [21] Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (13) : 6176 - 6193Zak, MarkMendonca, RohanBalazs, MercedeszBarrett, KathyBergeron, PhilippeBlair, Wade S.Chang, ChristineDeshmukh, GauriDeVoss, JasonDragovich, Peter S.Eigenbrot, CharlesGhilardi, NicoGibbons, PaulGradl, StefanHamman, ChrisHanan, Emily J.Harstad, EricHewitt, Peter R.Hurley, Christopher A.Jin, TianJohnson, AdamJohnson, TonyKenny, Jane R.Koehler, Michael F. T.Kohli, Pawan BirKulagowski, Janusz J.Labadie, SharadaLiao, JiangpengLiimatta, MaryaLin, ZhonghuaLupardus, Patrick J.Maxey, Robert J.Murray, Jeremy M.Pulk, RebeccaRodriguez, MadeleineSavage, ScottShia, StevenSteffek, MicahUbhayakar, SavitaUltsch, Markvan Abbema, AnneWard, Stuart I.Xiao, LingXiao, Yisong
- [22] Immunohistochemistry of Janus Kinase 1 (JAK1) Expression in VitiligoJOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, 2018, 52 (06) : 363 - 368Abdou, Asmaa GaberMaraee, AlaaYassien, HossamSarin, Mona
- [23] Efficacy of oral JAK1 or JAK1/2 inhibitor for treating refractory pruritus in dystrophic epidermolysis bullosa: A retrospective case seriesJOURNAL OF DERMATOLOGY, 2024, 51 (03) : 441 - 447Kwon, Il JooKim, Song-EeKim, Soo-ChanLee, Sang Eun
- [24] Prevention of Islet Inflammatory Stress with JAK1/JAK2 InhibitorsTRANSPLANTATION, 2018, 102 : S370 - S370Watson, EleanorWaibel, MichaelaTrivedi, PrerakPappas, EvanFynch, StaceySutherland, RobynKay, ThomasThomas, Helen
- [25] Dengue hemorrhagic fever is associated with polymorphisms in JAK1European Journal of Human Genetics, 2010, 18 : 1221 - 1227Luciano K SilvaRonald E BlantonAntonio R ParradoPaulo S MeloVanessa G MoratoEliana AG ReisJuarez P DiasJesuina M CastroPedro FC VasconcelosKatrina AB GoddardMaurício L BarretoMitermayer G ReisM Glória Teixeira
- [26] JAK1 Inhibition to Treat Crohn's DiseaseNEW ENGLAND JOURNAL OF MEDICINE, 2023, 388 (21) : 2005 - 2009Abreu, Maria T. T.
- [27] Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (11) : 4764 - 4785Zak, MarkHurley, Christopher A.Ward, Stuart I.Bergeron, PhilippeBarrett, KathyBalazs, MercedeszBlair, Wade S.Bull, RichardChakravarty, ParomaChang, ChristineCrackett, PeterDeshmukh, GauriDeVoss, JasonDragovich, Peter S.Eigenbrot, CharlesEllwood, CharlesGaines, SimonGhilardi, NicoGibbons, PaulGradl, StefanGribling, PeterHamman, ChrisHarstad, EricHewitt, PeterJohnson, AdamJohnson, TonyKenny, Jane R.Koehler, Michael F. T.Kohli, Pawan BirLabadie, SharadaLee, Wyne P.Liao, JiangpengLiimatta, MaryaMendonca, RohanNarukulla, RamanPulk, RebeccaReeve, AustinSavage, ScottShia, StevenSteffek, MicahUbhayakar, Savitavan Abbema, AnneAliagas, IgnacioAvitabile-Woo, BarbaraXiao, YisongYang, JingKulagowski, Janusz J.
- [28] Differential role of tyrosine phosphorylation in the regulation of JAK1 and JAK3.JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (01) : 1962 - 1962Liu, KDGreene, WCGoldsmith, MA
- [29] Preclinical characterization of JAK1/JAK2 inhibitors for treatment of type 1 diabetesEUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 361 - 361Scott, N. A.Trivedi, P. M.Graham, K. L.Fynch, S.Jenkins, M. R.Kay, T. W.Thomas, H. E.
- [30] STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinasesJOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 (10) : 2272 - 2280Mirmohammadsadegh, AlirezaHassan, MohamadBardenheuer, WalterMarini, AlessandraGustrau, AnnettNambiar, SandeepTannapfel, AndreaBojar, HansRuzicka, ThomasHengge, Ulrich R.