A NOVEL CYTOTOXIC MACROLIDE, SUPERSTOLIDE-B, RELATED TO SUPERSTOLIDE-A, FROM THE NEW CALEDONIAN MARINE SPONGE NEOSIPHONIA-SUPERSTES

被引：34

作者：

DAURIA, MV

PALOMA, LG

MINALE, L

ZAMPELLA, A

DEBITUS, C

机构：

[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM SOSTANZE NAT,I-80131 NAPLES,ITALY

[2] ORSTOM,NOUMEA,NEW CALEDONIA

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1994年 / 57卷 / 11期

关键词：

D O I：

10.1021/np50113a024

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The structure of a new cytotoxic macrolide, superstolide B [1], isolated from the deep water sponge Neosiphonia superstes, collected off New Caledonia, was elucidated mainly on the basis of nmr data. Compound 1 is closely related to superstolide A [2], a major cytotoxic component isolated from that organism, but lacks the 25-hydroxyl group found in 2 and has a C-24 (C-25)-double bond.

引用

页码：1595 / 1597

页数：3

共 3 条

[1] 2-DIMENSIONAL SPECTROSCOPY - APPLICATION TO NUCLEAR MAGNETIC-RESONANCE
AUE, WP
BARTHOLDI, E
ERNST, RR
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[2] SUPERSTOLIDE-A - A POTENT CYTOTOXIC MACROLIDE OF A NEW-TYPE FROM THE NEW-CALEDONIAN DEEP-WATER MARINE SPONGE NEOSIPHONIA-SUPERSTES
DAURIA, MV
DEBITUS, C
PALOMA, LG
MINALE, L
ZAMPELLA, A
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (15) : 6658 - 6663
[3] 3 NEW POTENT CYTOTOXIC MACROLIDES CLOSELY-RELATED TO SPHINXOLIDE FROM THE NEW CALEDONIAN SPONGE NEOSIPHONIA-SUPERSTES
DAURIA, MV
PALOMA, LG
MINALE, L
ZAMPELLA, A
VERBIST, JF
ROUSSAKIS, C
DEBITUS, C
[J]. TETRAHEDRON, 1993, 49 (38) : 8657 - 8664

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