MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY IN A MIXTURE OF TAURODEOXYCHOLIC ACID AND BETA-CYCLODEXTRIN

被引：53

作者：

OKAFO, GN ^{[1
]}

BINTZ, C ^{[1
]}

CLARKE, SE ^{[1
]}

CAMILLERI, P ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 17期

关键词：

D O I：

10.1039/c39920001189

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mixture of taurodeoxycholic acid and beta-cyclodextrin is found to form a 'pseudo-stationary' phase, which is very effective for the separation of the enantiomers of a variety of chiral compounds using micellar electrokinetic capillary chromatography (MECC); resolution is considerably superior to that obtained by using either taurodeoxycholic acid or beta-cyclodextrin alone.

引用

页码：1189 / 1192

页数：4

共 14 条

[1] DETERMINATION OF THE CRITICAL MICELLE CONCENTRATION OF SURFACTANTS USING THE FLUORESCENT-PROBE N-PHENYL-1-NAPHTHYLAMINE [J].

BRITO, RMM ;

VAZ, WLC .

ANALYTICAL BIOCHEMISTRY, 1986, 152 (02) :250-255

[2] SODIUM GLYCODEOXYCHOLATE AND TAURODEOXYCHOLATE - POSSIBLE HELICAL MODELS FOR CONJUGATED BILE-SALT MICELLES [J].

CAMPANELLI, AR ;

DESANCTIS, SC ;

CHIESSI, E ;

DALAGNI, M ;

GIGLIO, E ;

SCARAMUZZA, L .

JOURNAL OF PHYSICAL CHEMISTRY, 1989, 93 (04) :1536-1542

[3] BILE-SALT SURFACTANTS IN MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY - APPLICATION TO HYDROPHOBIC MOLECULE SEPARATIONS [J].

COLE, RO ;

SEPANIAK, MJ ;

HINZE, WL ;

GORSE, J ;

OLDIGES, K .

JOURNAL OF CHROMATOGRAPHY, 1991, 557 (1-2) :113-123

[4]

HOFMANN AF, 1973, BILE ACIDS, V2, P119

[5]

IONESCU LG, 1984, SURFACTANTS SOLUTION, V2, P789

[6]

KUPFER A, 1979, J PHARMACOL EXP THER, V209, P190

[7]

KUPFER A, 1981, J PHARMACOL EXP THER, V218, P193

[8]

Magid L, 1979, SOLUTION CHEM SURFAC, P427

[9]

NISHI H, 1990, J CHROMATOGR, V515, P223

[10]

NISHI H, 1990, ELECTROPHORESIS, V11, P91

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