SYNTHESIS OF 6-EPI-N-ACETYL-D-NEURAMINIC AND 4,6-BISEPI-N-ACETYL-D-NEURAMINIC ACID BY ALDOL CONDENSATION

被引：12
|
作者：
MACK, H [1 ]
BROSSMER, R [1 ]
机构：
[1] UNIV HEIDELBERG,INST BIOCHEM 2,IM NEUENHEIMER FELD 328,W-6900 HEIDELBERG,GERMANY
来源：
TETRAHEDRON LETTERS | 1992年 / 33卷 / 14期
关键词：
NEURAMINIC ACID ANALOGS; ALDOL CONDENSATION; CHAIN ELONGATION; OXAZOLINE-FURANOSES;
D O I：
10.1016/S0040-4039(00)74163-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of allofurano-2,3-oxazoline 2 with potassium ditert.butyl oxaloacetate afforded the two diastereomeric compounds 3 and 3a which, after deblocking and alkaline treatment, are converted to the two epimeric sialic acids 5 and 5a.
引用
收藏
页码：1867 / 1870
页数：4
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