SINGLE CELL-DNA CYTOPHOTOMETRY IN CLINICAL STAGE-I MALIGNANT-MELANOMA - RELATIONSHIP TO PROGNOSIS

被引：18
作者：
LINDHOLM, C
HOFER, PA
JONSSON, H
机构：
[1] UMEA UNIV,DEPT ONCOL,S-90187 UMEA,SWEDEN
[2] UMEA UNIV,DEPT PATHOL,S-90187 UMEA,SWEDEN
来源：
ACTA ONCOLOGICA | 1990年 / 29卷 / 02期
关键词：
DNA content; Malignant melanoma; Prognostic factors; Single cell cytophotometry; Skin;
D O I：
10.3109/02841869009126535
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Histological sections of 50 clinical stage I cutaneous melanomas were analyzed by single cell DNA cytophotometry. Forty-two percent of the melanomas had diploid modal values. Ploidy was not significantly related to the level of invasion, melanoma thickness or prognosis. These results are contradictory to published data from flow cytophotometry which, however, differ inter alia concerning patient materials and follow-up times. Mean nuclear area was in our study significantly correlated to the prognosis. ©1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：147 / 150
页数：4
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