INTESTINAL CALCIUM ABSORPTION - NATURE OF DEFECT IN CHRONIC RENAL DISEASE

被引:57
作者
AVIOLI, LV
SCOTT, S
LEE, SW
DELUCA, HF
机构
[1] Department of Medicine, Washington University School of Medicine, Jewish Hospital of St. Louis, St. Louis
[2] Department of Biochemistry, University of Wisconsin, Madison, WI
关键词
D O I
10.1126/science.166.3909.1154
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
When compared to that of normal animals, calcium-binding protein activity of duodenal mucosa obtained from uremic rats was decreased. There was no change in this activity after vitamin D3 therapy. In contrast, prior treatment with 25-hydroxycholecalciferol resulted in increased transport of calcium-45 and calcium-binding protein activity in the intestine.
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页码:1154 / &
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