Impacts of endometrioma type and two-different techniques of laparoscopic cystectomy on ovarian reserve by measuring anti-mullerian hormone concentration

被引:0
|
作者
Adnyana, Ida Bagus Putra [1 ]
机构
[1] Udayana Univ, Sanglah Gen Hosp Denpasar, Fac Med, Div Fertil Endocrinol & Reprod,Dept Obstet & Gyne, Bali, Indonesia
关键词
Endometrioma; stripping excision; AMH;
D O I
10.15562/bmj.v7i2.1149
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: Endometriosis caused chronic inflammation reaction, fibrosis, and adhesion resulting in anatomic distortion of pelvic organ commonly suffered by young woman. This study aims to understand the impact of the type of endometrioma and two different laparoscopic cystectomy excision techniques ("stripping" or complete excision vs. partial excision) on the ovarian reserve by measuring the antimullerian hormone (AMH) levels in patients with endometrioma. Method: This is an experimental study in the form of pre-test and post-test group design The subjects were patients with >3 cm endometrioma detected via transvaginal USG which were classified into two different groups, i.e., the "stripping" laparoscopic cystectomy group as control and partial excision laparoscopic cystectomy as an intervention group. Cystectomy techniques were chosen based on "formulated block sampling." The AMH levels measurements were performed before the operation (pre-test), and post-operation levels were measured at one and three months after the procedures on both groups. The study was conducted in Bali Royal Hospital (BROS), Denpasar, Indonesia, between January 2012 and January 2018. Independent sample t-test was used to analyze the collected data. Results: There was no significant difference in the age and length of marriage between the two groups (p>0.05). Unilateral endometrioma had higher concentration of AMH compared to bilateral endometrioma before the laparoscopy (2.09 +/- 1.33 vs 1.99 +/- 1.25 ng/ml; p=0.768), 1 month after the laparoscopy (1.20 +/- 0.59 vs 1.12 +/- 0.72 ng/ml; p=0.647), as well as 3 months after the laparoscopy (1.79 +/- 0.97 vs 1,44 +/- 0.87 ng/ml; p=0.148), but they were not statistically significant (p>0.05). Based on the laparoscopy techmgues, there's no significant difference in AMH concentration before laparoscopy (1.87 +/- 1.23 vs. 2.36 +/- 1.13; p= 0.119) in both groups. Otherwise, AMH level in partial excision laparoscopic cystectomy was significantly higher (p<0.05) than in the stripping laparoscopic cystectomy, one month after (1.33 +/- 0.62 vs. 0.98 +/- 0.67 ng/ml; p=0.038), as well as three months (1,88 +/- 0.97 vs. 1.29 +/- 0.77; p=0.011) after the surgery. Conclusion: Unilateral and bilateral endometriomas have no significant difference in AMH levels. There's also no significant difference of AMH levels before operation in both different cystectomy technique. Thus, it was found that the effect of partial excision laparoscopic cystectomy on AMH concentration was significantly lesser effect than in stripping laparoscopic cystectomy.
引用
收藏
页码:530 / 534
页数:5
相关论文
共 50 条
  • [31] Ovarian reserve in breast cancer: assessment with anti-Mullerian hormone
    Hamy, Anne-Sophie
    Porcher, Raphael
    Cuvier, Caroline
    Giacchetti, Sylvie
    Schlageter, Marie-Helene
    Coussieu, Christiane
    Gronier, Heloise
    Feugeas, Jean-Paul
    Adoui, Nadir
    Lacorte, Jean-Marc
    Poirot, Catherine
    Habdous, Mohamed
    Espie, Marc
    REPRODUCTIVE BIOMEDICINE ONLINE, 2014, 29 (05) : 573 - 580
  • [32] The Role of Anti-Mullerian Hormone (AMH) in Assessing Ovarian Reserve
    Tran, Nam D.
    Cedars, Marcelle I.
    Rosen, Mitchell P.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2011, 96 (12): : 3609 - 3614
  • [33] Anti-mullerian hormone and ovarian reserve in systemic lupus erythematosus
    Esteves Martins, Nadia Filipa
    Seixas, Maria Ines
    Pereira, Joaquim Polido
    Costa, Maria Manuela
    Fonseca, Joo Eurico
    CLINICAL RHEUMATOLOGY, 2017, 36 (12) : 2853 - 2854
  • [34] Evaluation of anti-Mullerian hormone as a test for the prediction of ovarian reserve
    Kwee, Janet
    Schats, Roel
    McDonnell, Joseph
    Themmen, Axel
    de Jong, Frank
    Lambalk, Cornelis
    FERTILITY AND STERILITY, 2008, 90 (03) : 737 - 743
  • [35] Anti-Mullerian Hormone and Ovarian Reserve in Systemic Lupus Erythematosus
    Mok, Chi Chiu
    Chan, Pak To
    To, Chi Hung
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S276 - S276
  • [36] Association of Myomectomy With Anti-Mullerian Hormone Levels and Ovarian Reserve
    Aharon, Devora
    Sekhon, Lucky
    Getrajdman, Chloe
    Naert, Mackenzie
    Hanley, William
    Kerr, Ahmad
    Ghofranian, Atoosa
    Hernandez-Nieto, Carlos
    Lee, Joseph A.
    Copperman, Alan
    Ascher-Walsh, Charles
    OBSTETRICS AND GYNECOLOGY, 2022, 140 (06): : 1000 - 1007
  • [37] Anti-mullerian hormone and ovarian reserve in systemic lupus erythematosus
    Mok, C. C.
    Chan, P. T.
    To, C. H.
    ARTHRITIS AND RHEUMATISM, 2013, 65 (01): : 206 - 210
  • [38] Association of Myomectomy with Anti-Mullerian Hormone Levels and Ovarian Reserve
    Liang, Xuzhi
    Fan, Jiangtao
    OBSTETRICS AND GYNECOLOGY, 2023, 141 (03): : 624 - 624
  • [39] Anti-Mullerian hormone, an ovarian reserve marker in hypogonadotropic hypogonadism
    Oncul, Mahmut
    Ozcivit, Ipek Betul
    Basibuyuk, Zafer
    Cebi, Ceren
    Sahmay, Sezai
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2022, 273 : 54 - 58
  • [40] Anti-Mullerian hormone levels following laparoscopic ovarian cystectomy with subcutaneous abdominal wall lifting for ovarian endometriomas
    Ono, Masataka
    Kojima, Junya
    Hasegawa, Ei
    Takaesu, Yotaro
    Sasaki, Toni
    Nishi, Hirotaka
    CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, 2021, 48 (01): : 91 - 97