LOCALIZATION OF GAMMA-AMINOBUTYRIC-ALPHA-OXOGLUTARIC ACID TRANSAMINASE IN MOUSE BRAIN

被引：64
作者：
WAKSMAN, A
RUBINSTEIN, MK
KURIYAMA, K
ROBERTS, E
机构：
[1] Department of Biochemistry, City of Hope Medical Center, Duarte, California
来源：
JOURNAL OF NEUROCHEMISTRY | 1968年 / 15卷 / 04期
关键词：
D O I：
10.1111/j.1471-4159.1968.tb11620.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The distribution of γ‐aminobutyric‐α‐oxoglutarate transaminase (GABA‐T) has been studied in mouse brain by histochemical visualization on sections, quantitative determination in grossly dissected brain regions, and in subcellular fractions prepared from whole brain homogenates. The results indicate that GABA‐T is predominantly a mitochondrial enzyme and that its concentration is particularly high in brain stem areas. The results are discussed in relation to the overall function of the GABA system in the CNS. Copyright © 1968, Wiley Blackwell. All rights reserved
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页码：351 / +
页数：1
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