LACK OF EFFECT OF SUPPLEMENTAL DIETARY SELENIUM ON TIME TO DEVELOPMENT OF RADIATION-INDUCED CUTANEOUS TUMORS IN RATS

被引：2

作者：

ZACKHEIM, HS ^{[1
]}

FU, KK ^{[1
]}

CHAN, AS ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT RADIAT ONCOL, SAN FRANCISCO, CA 94143 USA

来源：

CANCER LETTERS | 1993年 / 70卷 / 1-2期

关键词：

CHEMOPREVENTION; ELECTRON BEAM IRRADIATION; SKIN; RAT;

D O I：

10.1016/0304-3835(93)90084-M

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Sprague-Dawley 8-week-old male rats received a single dose of 1425 cGy to the skin of the back using a 6 meV electron beam. Three days later they were randomized into three groups receiving supplemental dietary selenium as sodium selenite at levels of 0 ppm, 1 ppm, and 2 ppm selenium. Cutaneous tumors first appeared 33 weeks after irradiation and the experiment was terminated at 63 weeks. A wide variety of epithelial and connective tissue tumors developed. There was no significnt difference in the time to development of epithelial or connective tissue tumors between the three groups. Thus, under the conditions of this experiment an inhibitory effect of dietary selenium on radiation-induced skin tumors was not evident.

引用

页码：123 / 127

页数：5

共 50 条

[31] Effect of dietary selenium intake on radiation induced oxidative stress in erythrocites
Dujic, I
Stankov, OJ
Demajo, M
IRPA9 - 1996 INTERNATIONAL CONGRESS ON RADIATION PROTECTION / NINTH INTERNATIONAL CONGRESS OF THE INTERNATIONAL RADIATION PROTECTION ASSOCIATION, PROCEEDINGS, VOL 4, 1996, : D113 - D113
[32] Dietary selenium supplementation prolongs survival and ameliorates thoracic radiation-induced lung fibrosis in mice
Christofidou-Solomidou, M
Solomides, C
Workman, A
Arguiri, E
Kristina, HI
Cengel, K
FASEB JOURNAL, 2006, 20 (05): : A1068 - A1068
[33] HIGH DIETARY SELENIUM INCREASES RADIATION-INDUCED MICRONUCLEUS FORMATION IN MOUSE BONE-MARROW
KNUUTILA, S
ERIKSSON, J
JUVONEN, E
KOVANEN, R
LUOTOLA, J
WESTERMARCK, T
HEREDITAS, 1985, 102 (02) : 237 - 239
[34] Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats
Wiegman, EA
van Gameren, MA
Kampinga, HH
Szabó, BG
Coppes, RP
RADIOTHERAPY AND ONCOLOGY, 2004, 72 (01) : 67 - 70
[35] EFFECT OF PROSPIDIN ON DEVELOPMENT OF INDUCED TUMORS IN RATS
SOKOLOVA, AS
MANDRIK, EV
CHERNOV, VA
VOPROSY ONKOLOGII, 1976, 22 (06) : 96 - 96
[36] PREVENTION OF SPONTANEOUS AND RADIATION-INDUCED TUMORS IN RATS BY REDUCTION OF FOOD-INTAKE
GROSS, L
DREYFUSS, Y
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (17) : 6795 - 6797
[37] The effect of ethanolic extract of propolis on radiation-induced mucositis in rats
Ghassemi, Leila
Zabihi, Ebrahim
Mahdavi, Rabi
Seyedmajidi, Maryam
Akram, Sadat
Motallebnejad, Mina
SAUDI MEDICAL JOURNAL, 2010, 31 (06) : 622 - 626
[38] Evaluation of the effect of selenium on radiation-induced toxicities in head neck cancer patients
Buentzel, J.
Micke, O.
Glatzel, M.
Bruns, F.
Kisters, K.
Muecke, R.
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
[39] Radioprotective effect of Date syrup on radiation-induced damage in Rats
Abou-Zeid, Shimaa M.
El-bialy, Badr E.
El-borai, Nermeen B.
AbuBakr, Huda O.
Elhadary, Abdel Monsef A.
SCIENTIFIC REPORTS, 2018, 8
[40] EFFECT OF PITUITARY EXTRACTS ON RADIATION-INDUCED TESTICULAR ATROPHY IN RATS
STORER, JB
SANDERS, P
PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1953, 83 (02): : 259 - 262

← 1 2 3 4 5 →