THE ADSORPTION MECHANISM OF REGULATION OF HEXOKINASE-ACTIVITY IN RAT SARCOMA M-1

被引:0
|
作者
GARKUSHA, NF
GONCHAROVA, NY
机构
关键词
HEXOKINASE; SARCOMA M-1; ADSORPTION MECHANISM OF REGULATION OF HEXOKINASE ACTIVITY; COMPLEX OF HEXOKINASE WITH MITOCHONDRIAL MEMBRANES;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The peculiarities of the interaction of hexokinase with mitochondrial membranes in rat sarcoma M-1 were investigated. The conditions of formation and strength of the complex of the enzyme with the membranes, as well as the kinetic parameters of hexokinase in the free state and in the enzyme-membrane complex, were characterized. The data obtained are discussed as applied to the concept of the adsorption mechanism of regulation of the hexokinase activity in tumor tissue.
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页码:1197 / 1202
页数:6
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