DETERMINATION OF ZOMEPIRAC IN PLASMA BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY

被引：22
|
作者：
NG, KT
SNYDERMAN, T
机构：
[1] McNeil Laboratories, Fort Washington, PA 19034
来源：
JOURNAL OF CHROMATOGRAPHY | 1979年 / 178卷 / 01期
关键词：
D O I：
10.1016/S0021-9673(00)89712-5
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A sensitive, specific and precise high-pressure liquid-chromatographic method for the determination of the analgesic agent, zomepirac, in plasma samples is described. The lowest concentration of zomepirac that can be measured accurately and precisely (coefficient of variation <20%) in a 2-ml plasma sample is 10 ng/ml. The standard curve is linear in the concentration range of 10 to 5000 ng/ml. To date, this procedure has been employed successfully in analysing over 10,000 clinical plasma samples. © 1979.
引用
收藏
页码：241 / 247
页数：7
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