DISTRIBUTION OF MYOSIN MESSENGER-RNA DURING DEVELOPMENT AND REGENERATION OF SKELETAL-MUSCLE FIBERS

被引：21

作者：

DIX, DJ ^{[1
]}

EISENBERG, BR ^{[1
]}

机构：

[1] UNIV ILLINOIS,DEPT PHYSIOL & BIOPHYS,M-C 901,POB 6998,CHICAGO,IL 60680

来源：

DEVELOPMENTAL BIOLOGY | 1991年 / 143卷 / 02期

关键词：

D O I：

10.1016/0012-1606(91)90093-I

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Myosin mRNA distribution among subcellular compartments of anterior tibialis muscles in rabbit is monitored by in situ hybridization. A high density of mRNA was widely distributed throughout myotubes from 29-day fetal muscle and from regenerating adult muscle. All cytoplasmic spaces contained mRNA except where scattered myofibrils and centrally located nuclei were found. In fibers from 22-week-old rabbits, myosin mRNA was concentrated under the sarcolemma and excluded from the consolidated myofibrils and peripheral nuclei. The dispersal of mRNA through the cytoplasm in myotubes suggests that translation of myosin is widespread and that rapid myofibril assembly can occur throughout the fiber. © 1991.

引用

页码：422 / 426

页数：5

共 23 条

[1] LOCALIZATION OF AN ACETYLCHOLINE-RECEPTOR INTRON TO THE NUCLEAR-MEMBRANE [J].

BERMAN, SA ;

BURSZTAJN, S ;

BOWEN, B ;

GILBERT, W .

SCIENCE, 1990, 247 (4939) :212-214

[2]

BISCHOFF R, 1990, CELL BIOL, V111, P201

[3] EXPRESSION OF MYOSIN HEAVY-CHAIN ISOFORMS IN REGENERATING MYOTUBES OF INNERVATED AND DENERVATED CHICKEN PECTORAL MUSCLE [J].

CERNY, LC ;

BANDMAN, E .

DEVELOPMENTAL BIOLOGY, 1987, 119 (02) :350-362

[4] GAMMA ACTIN, SPECTRIN, AND INTERMEDIATE FILAMENT PROTEINS COLOCALIZE WITH VINCULIN AT COSTAMERES, MYOFIBRIL-TO-SARCOLEMMA ATTACHMENT SITES [J].

CRAIG, SW ;

PARDO, JV .

CELL MOTILITY AND THE CYTOSKELETON, 1983, 3 (5-6) :449-462

[5]

DIX DJ, 1991, IN PRESS CELL TISSUE

[6]

DIX DJ, 1988, J HISTOCHEM CYTOCHEM, V6, P1519

[7]

DIX DJ, 1990, J CELL BIOL, V111, P1884

[8]

EISENBERG BR, 1991, IN PRESS J MOL CELL

[9] LOCALIZATION OF NICOTINIC ACETYLCHOLINE-RECEPTOR ALPHA-SUBUNIT TRANSCRIPTS DURING MYOGENESIS AND MOTOR ENDPLATE DEVELOPMENT IN THE CHICK [J].

FONTAINE, B ;

CHANGEUX, JP .

JOURNAL OF CELL BIOLOGY, 1989, 108 (03) :1025-1037

[10] COTRANSLATIONAL ASSEMBLY OF MYOSIN HEAVY-CHAIN IN DEVELOPING CULTURED SKELETAL-MUSCLE [J].

ISAACS, WB ;

FULTON, AB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (17) :6174-6178

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