STEREOCONTROL IN THE INTRAMOLECULAR NITRONE CYCLOADDITION TO VINYL SULFUR DERIVATIVES

被引：7

作者：

ANNUNZIATA, R ^{[1
]}

CINQUINI, M ^{[1
]}

COZZI, F ^{[1
]}

GIARONI, P ^{[1
]}

RAIMONDI, L ^{[1
]}

机构：

[1] UNIV MILAN,DIPARTIMENTO CHIM ORGAN & IND,I-20133 MILAN,ITALY

来源：

TETRAHEDRON-ASYMMETRY | 1990年 / 1卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(00)86330-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The intramolecular cycloaddition to vinyl sulphur derivatives of a series of nitrones featuring an alkyl or alkoxy substituted α-stereocenter on the tether connecting dipole and dipolarophile occurs in a completely stereoselective fashion to give 3′,3-anti configurated products. The synthetic potentialities of this reaction is illustrated by the synthesis of a precursor of (d)-biotin. © 1990.

引用

页码：251 / 264

页数：14

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