MORPHINE PRE-SYNAPTICALLY INHIBITS A GANGLIONIC CHOLINERGIC SYNAPSE

被引：40

作者：

BORNSTEIN, JC

FIELDS, HL

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT NEUROL, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF SAN FRANCISCO, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA

来源：

NEUROSCIENCE LETTERS | 1979年 / 15卷 / 01期

关键词：

D O I：

10.1016/0304-3940(79)91532-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of morphine on synaptic transmission through the inferior mesenteric ganglion (IMG) were studied using intracellular recording techniques. Morphine produced a reversible, dose-dependent reduction in ther quantal content of the synaptic potentials with little or no effect on quantal size or the properties of the ganglion cells. This effect of morphine was antagonized by naloxone suggesting the presence of specific preganglionic opiate receptors. © 1979.

引用

页码：77 / 82

页数：6

共 16 条

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