ALCOHOL-INDUCED MALABSORPTION OF VITAMIN B12 IN MAN

被引：109

作者：

LINDENBA.J

LIEBER, CS

机构：

[1] Department of Medicine, Columbia University

[2] Department of Medicine, Mount Sinai School of Medicine

[3] Section of Liver Disease and Nutrition, Bronx Veterans Administration Hospital

来源：

NATURE | 1969年 / 224卷 / 5221期

关键词：

D O I：

10.1038/224806a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

INTOXICATION with alcohol is frequently associated with diarrhoea, and disturbances of intestinal function have been reported to be common in chronic alcoholics studied shortly after drinking-bouts1-5. Because the normal diet of alcoholics is characteristically poor, it is not clear whether the transient malabsorption frequently found can be attributed to a direct toxic effect of ethanol on the small intestine, or to a nutritional deficiency. We therefore studied the effects of the experimental ingestion of ethanol in man on vitamin B12 absorption under controlled metabolic ward conditions in the absence of nutritional deficiency. © 1969 Nature Publishing Group.

引用

页码：806 / &

共 12 条

[1] EFFECT OF ETHANOL AND OTHER ALCOHOLS ON TRANSPORT OF AMINO ACIDS AND GLUCOSE BY EVERTED SACS OF RAT SMALL INTESTINE [J].