FOTEMUSTINE IN PATIENTS WITH RELAPSING MALIGNANT GLIOMAS - A PHASE-II TRIAL

被引：0

作者：

PUNT, CJA

STAMATAKIS, L

GERARD, B

机构：

[1] INST RECH INT SERV,BRUSSELS,BELGIUM

[2] CTR HOSP TIVOLI,LA LOUVIERE,BELGIUM

来源：

ONCOLOGY REPORTS | 1995年 / 2卷 / 02期

关键词：

BRAIN TUMORS; GLIOMA; ASTROCYTOMA; GLIOBLASTOMA MULTIFORME; CHEMOTHERAPY; FOTEMUSTINE;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Eleven patients with relapsing malignant glioma were treated with fotemustine chemotherapy, a new nitrosourea derivative. One partial response of 13 months duration occurred, resulting in a marked improvement of the quality of life of the patient. Seven patients had stable disease for a median duration of 5 months. Median survival from inclusion in the study was 6 months. Toxicity was mainly hematologic and manageable. We confirm that fotemustine has some activity in patients with relapsing malignant glioma.

引用

页码：307 / 308

页数：2

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