Non-Invasive Assessment of Non-Alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography

被引:15
作者
Berzigotti, Annalisa [1 ]
机构
[1] Univ Barcelona, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Barcelona Hepat Hemodynam Lab,Liver Unit,Hosp Cli, Barcelona, Spain
关键词
ARFI; cirrhosis; controlled attenuation parameter; liver fibrosis; NASH; sonography;
D O I
10.2174/1574887109666141216101630
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Non-alcoholic fatty liver disease (NAFLD) is extremely prevalent in the Western world. Non-invasive diagnostic methods should be able to reflect the presence and severity of liver fatty changes and the presence and severity of hepatic inflammation and fibrosis (features of non-alcoholic steato-hepatitis), since these are related to the risk of progression and clinical complications. This article will: a) review the rational basis for the use of ultrasound and transient elastography in patients with NAFLD; b) summarize available data regarding the diagnostic performance of these two widely used non-invasive imaging methods in patients with NAFLD; and c) give an overview of newer sonographic applications that might be used in clinical practice in the near future in this field.
引用
收藏
页码:170 / 177
页数:8
相关论文
共 68 条
[1]   Transient elastography in non-alcoholic fatty liver disease [J].
Abenavoli, Ludovico ;
Beaugrand, Michel .
ANNALS OF HEPATOLOGY, 2012, 11 (02) :172-178
[2]   Nonalcoholic fatty liver disease [J].
Brunt, Elizabeth M. ;
Wong, Vincent W. -S. ;
Nobili, Valerio ;
Day, Christopher P. ;
Sookoian, Silvia ;
Maher, Jacquelyn J. ;
Bugianesi, Elisabetta ;
Sirlin, Claude B. ;
Neuschwander-Tetri, BrentA. ;
Rinella, Mary E. .
NATURE REVIEWS DISEASE PRIMERS, 2015, 1
[3]   Effects of diffuse fatty infiltration of the liver on portal vein flow hemodynamics [J].
Balci, Ali ;
Karazincir, Sinem ;
Sumbas, HaIdun ;
Oter, Yasemin ;
Egilmez, Ertugrud ;
Inandi, Tacettin .
JOURNAL OF CLINICAL ULTRASOUND, 2008, 36 (03) :134-140
[4]   Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD [J].
Ballestri, Stefano ;
Lonardo, Amedeo ;
Romagnoli, Dante ;
Carulli, Lucia ;
Losi, Luisa ;
Day, Christopher P. ;
Loria, Paola .
LIVER INTERNATIONAL, 2012, 32 (08) :1242-1252
[5]   Getting closer to a point-of-care diagnostic assessment in patients with chronic liver disease: Controlled attenuation parameter for steatosis [J].
Berzigotti, Annalisa .
JOURNAL OF HEPATOLOGY, 2014, 60 (05) :910-912
[6]   Ultrasonographic evaluation of liver surface and transient elastography in clinically doubtful cirrhosis [J].
Berzigotti, Annalisa ;
Abraldes, Juan G. ;
Tandon, Puneeta ;
Erice, Eva ;
Gilabert, Rosa ;
Carlos Garcia-Pagan, Juan ;
Bosch, Jaime .
JOURNAL OF HEPATOLOGY, 2010, 52 (06) :846-853
[7]   Ultrasound in Portal Hypertension - Part 2-and EFSUMB Recommendations for the Performance and Reporting of Ultrasound Examinations in Portal Hypertension [J].
Berzigottil, A. ;
Piscaglia, F. .
ULTRASCHALL IN DER MEDIZIN, 2012, 33 (01) :8-29
[8]  
Carvalhana S, 2013, LIVER INT
[9]   Noninvasive Methods to Assess Liver Disease in Patients With Hepatitis B or C [J].
Castera, Laurent .
GASTROENTEROLOGY, 2012, 142 (06) :1293-+
[10]   Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States [J].
Charlton, Michael R. ;
Burns, Justin M. ;
Pedersen, Rachel A. ;
Watt, Kymberly D. ;
Heimbach, Julie K. ;
Dierkhising, Ross A. .
GASTROENTEROLOGY, 2011, 141 (04) :1249-1253