URINARY-BLADDER CARCINOMA PRODUCING GRANULOCYTE-COLONY-STIMULATING FACTOR (G-CSF) - A CASE-REPORT WITH IMMUNOHISTOCHEMISTRY

被引：13

作者：

ITO, T

SHIMAMURA, K

SHOJI, K

AKATSUKA, A

KIRYU, Y

TAMAOKI, N

OSAMURA, Y

机构：

[1] TOKAI UNIV,SCH MED,DEPT PATHOL,ISEHARA,KANAGAWA 25911,JAPAN

[2] NIPPON KOKAN LTD CO HOSP,DIV INTERNAL MED,KAWASAKI KU,KAWASAKI,KANAGAWA 210,JAPAN

[3] NIPPON KOKAN LTD CO HOSP,DIV UROL,KAWASAKI KU,KAWASAKI,KANAGAWA 210,JAPAN

[4] TOKAI UNIV,SCH MED,DIV ELECTRON MICROSCOPY,ISEHARA,KANAGAWA 25911,JAPAN

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1993年 / 422卷 / 06期

关键词：

URINARY BLADDER CARCINOMA; GRANULOCYTOSIS; GRANULOCYTE COLONY STIMULATING FACTOR;

D O I：

10.1007/BF01606458

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

A rare case of urinary bladder carcinoma with granulocyte colony stimulating factor (G-CSF) production was reported. In an 83-year-old female, marked neutrophilia in the peripheral blood decreased from 132,500/mm3 to 3,300/mm3 after tumour resection. The tumour was a transitional cell carcinoma. The serum G-CSF level reduced from 238 pg/ml pre-operatively to normal (60 pg/ml) after the operation. Immunohistochemical investigation of the resected tumour with monoclonal antibody specific for G-CSF revealed positive staining in the carcinoma cells, confirming G-CSF secretion.

引用

页码：487 / 490

页数：4

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