Novel synthesis, characterization and antimicrobial activity of some new 3, 5-diarylpyrazolines

被引:0
|
作者
Bhise, M. P. [1 ]
Raut, V. M. [1 ]
Pawar, R. P. [1 ]
Gulwade, G. P. [1 ]
Junghare, N. A. [2 ]
Murhekar, G. H. [1 ]
机构
[1] Govt Vidarbha Inst Sci & Humanities, Dept Chem, Amravati, India
[2] MCTs Rajiv Gandhi Inst Technol, Andheri W Mumbai, India
关键词
3-(2-Hydroxyphenyl)-4-aroyl-5-arylpyrazoline; Antimicrobial activity;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
3-Aroyl flavanones were allowed to react with hydrazine hydrate in dioxane containing little piperidine to give corresponding 3-(2-hydroxyphenyl)-4-aroyl-5-arylpyrazolines. Their structural assignment are based on elemental analysis, spectral data (IR, UV & NMR) and chemical properties. All these compounds were tested in vitro for their antibacterial activity by disk-diffusion method against gram positive and gram negative bacterias. In some of the compounds the results are found to be encouraging.
引用
收藏
页码:1065 / 1069
页数:5
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