HEREDITARY OVARIAN-CANCER - A DILEMMA IN PROGNOSIS

被引:0
作者
KLEIN, B
LURIE, H
STEIN, M
KUTEN, A
STEINHERZ, R
机构
[1] BEILINSON MED CTR, DEPT BIOCHEM GENET, IL-49100 PETAH TIQWA, ISRAEL
[2] TEL AVIV UNIV, SACKLER FAC MED, IL-69978 TEL AVIV, ISRAEL
[3] RAMBAM MED CTR, NO ISRAEL ONCOL CTR, HAIFA, ISRAEL
来源
ISRAEL JOURNAL OF MEDICAL SCIENCES | 1992年 / 28卷 / 01期
关键词
HEREDITARY OVARIAN CANCER; PROPHYLACTIC OOPHORECTOMY; CANCER-PRONE SYNDROMES;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Five women in three generations developed ovarian cancer. We closely monitored 36 descendent women in this family who were at high risk for developing this disease. Prophylactic oophorectomy is considered the optimal way to prevent the development of ovarian cancer. In the light of the young age of the women at risk and their strong objection to oophorectomy, we closely monitored the examinees for early signs of cancer for more than 5 years. None of them developed cancer. The dilemma in treatment of women at risk is discussed.
引用
收藏
页码:16 / 19
页数:4
相关论文
共 50 条
  • [41] Hereditary ovarian carcinoma: Heterogeneity, molecular genetics, pathology, and management
    Lynch, Henry T.
    Casey, Murray Joseph
    Snyder, Carrie L.
    Bewtra, Chhanda
    Lynch, Jane F.
    Butts, Matthew
    Godwin, Andrew K.
    MOLECULAR ONCOLOGY, 2009, 3 (02) : 97 - 137
  • [42] Mullerian intra-abdominal carcinomatosis in hereditary breast ovarian cancer syndrome: implications for risk-reducing surgery
    Casey, Murray Joseph
    Colanta, Agnes B.
    FAMILIAL CANCER, 2016, 15 (03) : 371 - 384
  • [43] Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan
    D. S. Prokofyeva
    E. T. Mingazheva
    Ya. V. Valova
    D. D. Sakaeva
    R. R. Faishanova
    A. Kh. Nurgalieva
    R. R. Valiev
    N. Bogdanova
    T. Dörk
    E. K. Khusnutdinova
    Journal of Ovarian Research, 16
  • [44] Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan
    Prokofyeva, D. S.
    Mingazheva, E. T.
    Valova, Ya. V.
    Sakaeva, D. D.
    Faishanova, R. R.
    Nurgalieva, A. Kh.
    Valiev, R. R.
    Bogdanova, N.
    Doerk, T.
    Khusnutdinova, E. K.
    JOURNAL OF OVARIAN RESEARCH, 2023, 16 (01)
  • [45] Hereditary ovarian carcinomas: clinico-biological features and treatment
    Floquet, Anne
    Stoeckle, Eberhard
    Croce, Sabrina
    Longy, Michel
    Mc Grogan, Gaetan
    Barouk, Emmanuelle
    Bubien, Virginie
    Garbay, Delphine
    Joly, Eglantine
    Guyon, Frederic
    BULLETIN DU CANCER, 2014, 101 (02) : 167 - 174
  • [46] The Preventive Intervention of Hereditary Breast Cancer
    Cao, Ayong
    Huang, Liang
    Shao, Zhimin
    TRANSLATIONAL RESEARCH IN BREAST CANCER: BIOMARKER DIAGNOSIS, TARGETED THERAPIES AND APPROACHES TO PRECISION MEDICINE, 2017, 1026 : 41 - 57
  • [47] Familial ovarian cancer and early ovarian cancer: Biologic, pathologic, and clinical features
    Werness, BA
    Eltabbakh, GH
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2001, 20 (01) : 48 - 63
  • [48] Current update on the molecular genetics and management of hereditary ovarian cancers: a primer for radiologists
    Malak Itani
    Neeraj Lalwani
    Dhakshinamoorthy Ganeshan
    Maria Zulfiqar
    Cary Siegel
    Abdominal Radiology, 2021, 46 : 2281 - 2292
  • [49] Current update on the molecular genetics and management of hereditary ovarian cancers: a primer for radiologists
    Itani, Malak
    Lalwani, Neeraj
    Ganeshan, Dhakshinamoorthy
    Zulfiqar, Maria
    Siegel, Cary
    ABDOMINAL RADIOLOGY, 2021, 46 (06) : 2281 - 2292
  • [50] Breast Cancer and Ovarian Cancer Genetics: An Update
    Edlich, Richard F.
    Cross, Catherine L.
    Wack, Courtney A.
    Chase, Margot E.
    Lin, Kant Y.
    Long, William B., III
    JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY, 2008, 27 (04) : 245 - 256