A Case of IgG4-Related Lung Disease Presenting as Interstitial Lung Disease

被引：12

作者：

Ahn, Jee Hwan ^{[1
]}

Hong, Sun In ^{[1
]}

Cho, Dong Hui ^{[1
]}

Chae, Eun Jin ^{[2
]}

Song, Joon Seon ^{[3
]}

Song, Jin Woo ^{[1
]}

机构：

[1] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Internal Med, Seoul, South Korea

[2] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Radiol, Seoul, South Korea

[3] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Pathol, Seoul, South Korea

来源：

TUBERCULOSIS AND RESPIRATORY DISEASES | 2014年 / 77卷 / 02期

关键词：

IgG4; Lung Diseases; Interstitialmediastinal;

D O I：

10.4046/trd.2014.77.2.85

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Intrathoracic involvement of immunoglobulin G4 (IgG4)-related disease has recently been reported. However, a subset of the disease presenting as interstitial lung disease is rare. Here, we report a case of a 35-year-old man with IgG4-related lung disease with manifestations similar to those of interstitial lung disease. Chest computed tomography showed diffuse ground glass opacities and rapidly progressive pleural and subpleural fibrosis in both upper lobes. Histological findings showed diffuse interstitial lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. Serum levels of IgG and IgG4 were also increased. The patient was diagnosed with IgG4-related lung disease, treated with antiinflammatory agents, and showed improvement. Lung involvement of IgG4-related disease can present as interstitial lung disease and, therefore, should be differentiated when evaluating interstitial lung disease.

引用

页码：85 / 89

页数：5

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