A CASE OF GRAVES-DISEASE AND PAPILLARY THYROID-CARCINOMA WITH PREDOMINANT PRODUCTION OF THYROID-STIMULATION-BLOCKING ANTIBODIES (TSBAB) PERSISTED AFTER TOTAL THYROIDECTOMY

被引：0

作者：

NAKAMURA, S

ISHIYAMATAKUNO, M

KOSAKA, J

KONDO, K

HORIYA, Y

HARA, S

SHIMA, H

SHIRAKI, T

机构：

[1] GIFU RED CROSS HOSP,DEPT SURG,GIFU 502,JAPAN

[2] GIFU RED CROSS HOSP,DEPT PATHOL,GIFU 502,JAPAN

[3] NATL SANAT GIFU HOSP,DEPT RESP DIS,GIFU 500,JAPAN

来源：

ENDOCRINOLOGIA JAPONICA | 1992年 / 39卷 / 01期

关键词：

GRAVES DISEASE; PAPILLARY THYROID CARCINOMA; TOTAL THYROIDECTOMY; THYROID-STIMULATING ANTIBODIES; THYROID-STIMULATION-BLOCKING ANTIBODIES;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 42-year-old female with Graves' disease and papillary thyroid carcinoma with lung metastasis was referred to our hospital. After treatment of thyrotoxicosis with methimazole and Lugol's solution, she underwent total thyroidectomy. She was then given I-131 twice to treat lung metastasis. However, I-131 uptake into the lung was not clear in the scintigram. Both thyroid-stimulating antibodies (TSAb) and thyroid-stimulation-blocking antibodies (TSBAb) were detected in her sera before and after the treatments. Compared with TSAb activities, TSBAb activities were extremely high. Changes in the titers of these two antibodies were not clear after total thyroidectomy. These results indicate that lymphocytes outside the thyroid gland are the major source of TSAb and TSBAb in this patient.

引用

页码：133 / 139

页数：7

共 25 条

[1] THE ACUTE CHANGES IN THYROID STIMULATING IMMUNOGLOBULINS, THYROGLOBULIN AND THYROGLOBULIN ANTIBODIES FOLLOWING SUBTOTAL THYROIDECTOMY [J].