NUCLEOTIDE-SEQUENCE OF A CDNA CODING FOR THE MITOCHONDRIAL PRECURSOR PROTEIN OF CYTOCHROME-C-OXIDASE SUBUNIT-IV FROM THE SLIME-MOLD DICTYOSTELIUM-DISCOIDEUM

被引：0
|
作者：
RIZZUTO, R
SANDONA, D
CAPALDI, RA
BISSON, R
机构：
[1] UNIV PADUA,IST PATOL GEN,PATOL & BIOL MOLEC LAB,VIA TRIESTE 75,I-35121 PADUA,ITALY
[2] UNIV OREGON,INST MOLEC BIOL,EUGENE,OR 97403
[3] UNIV PADUA,CNR,CTR STUDI FISIOL MITOCONDRI,I-35100 PADUA,ITALY
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1991年 / 1090卷 / 01期
关键词：
CYTOCHROME-C OXIDASE; SUBUNIT-IV; CDNA; NUCLEOTIDE SEQUENCE; CLEAVABLE PRESEQUENCE; MITOCHONDRION; (DICTYOSTELIUM-DISCOIDEUM);
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Subunit-specific polyclonal antibodies were used to isolate cDNA clones encoding subunit IV of Dictyostelium discoideum cytochrome c oxidase. DNA sequence analysis reveals an open reading frame of 149 amino acids. As shown by sequencing of the protein N-terminus, the subunit is synthesized with a 24 residue cleavable presequence which leads to a mature polypeptide of 14305 Da. The slime mold subunit exhibits a low but significant degree of similarity with subunit Va of human and subunit VI of yeast cytochrome c oxidase.
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页码：125 / 128
页数：4
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