FINE-NEEDLE ASPIRATION CYTOLOGY OF GRANULOCYTIC SARCOMA AND MYELOID METAPLASIA

被引：19
作者：
SILVERMAN, JF
GEISINGER, KR
PARK, HK
STRAUSBAUCH, PR
FRABLE, WJ
机构：
[1] Department of Clinical Pathology and Diagnostic Medicine, East Carolina University School of Medicine, Greenville, North Carolina
[2] Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina
[3] Department of Surgical Pathology and Cytopathology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
来源：
DIAGNOSTIC CYTOPATHOLOGY | 1990年 / 6卷 / 02期
关键词：
Extramedullary hematopoiesis; Fine‐needle aspiration cytology; Granulocytic sarcoma; Myeloid metaplasia; Myeloproliferative disorde;
D O I：
10.1002/dc.2840060207
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The fine‐needle aspiration (FNA) cytology of two cases of granulocytic sarcoma involving the breast is reported along with the FNA cytology of one case of myeloid metaplasia (extramedullary hematopoiesis) involving an axillalry lymph node. Two patients had known myeloproliferative disorders, while granulocytic sarcoma of the breast was the initial presentation of an unsuspected acute granulocytic leukemia in the other patient. Diff‐Quik‐stained preparations aided in the diagnosis of all three cases. Immunoperoxidase stains for factor VIII‐related antigen helped confirm the megakaryocytic differentiation of the cells in the FNA cytology of myeloid metaplasia. Electron microscopic (EM) examination performed on the aspirated material also showed megakaryocytic differentiation of the bizarre cells. FNA cytology can make a specific diagnosis of granulocytic sarcoma and myeloid metaplasia. The workup of these unusual extramedullary myeloproliferative masses was aided when immunocytochemistry and EM were performed on the aspirated material. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
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页码：106 / 111
页数：6
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