SYNTHESIS OF SOME 2-[(5'-ARYL-1',3',4'-OXADIAZOL-2-YL)AMINO]-1,3-HETERAZOLES AS POTENTIAL PESTICIDES

Some new 2-[(5'-aryl-1',3',4'-oxadiazol-2-yl)amino]-1,3-heterazoles III—VII were synthesized by reacting synthons, N-(5-aryl-1, 3, 4-oxadiazol-2-yl)carbonimidodithioates II with ortho-disubstituted aromatic and 1,2-disubstituted aliphatic dinucleophiles. The requisite synthons were prepared by reacting 2-amino-5-aryl-1, 3, 4-oxadiazoles I with carbon disulfide and methyl iodide in the presence of concentrated aqueous sodium hydroxide. Antibacterial and antifungal activities of some of the representative compounds are reported. © 1990, American Chemical Society. All rights reserved.