MOLECULAR DETECTION OF CANINE DISTEMPER VIRUS IN CLINICAL CASES FROM UNVACCINATED DOMESTIC DOGS AND ASSESSMENT OF RISK FACTORS

被引：1

作者：

Soto R, Andrea ^{[1
]}

Luna E., Luis R. ^{[1
]}

Rosadio A, Raul ^{[1
]}

Maturrano H, Lenin ^{[2
]}

机构：

[1] Univ Nacl Mayor San Marcos, Fac Med Vet, Lab Microbiol & Parasitol Vet, Lima, Peru

[2] Univ Nacl Mayor San Marcos, Fac Med Vet, Lab Zootecnia & Prod Agr, Lima, Peru

来源：

REVISTA DE INVESTIGACIONES VETERINARIAS DEL PERU | 2018年 / 29卷 / 03期

关键词：

canine distemper; molecular detection; nucleoprotein; PCR;

D O I：

10.15381/rivep.v29i3.14744

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The canine distemper (CD) is a viral infection caused by a Morbillivirus of the family Paramyxoviridae. It can generate digestive, respiratory, and nervous symptomatology, depending on the infecting strain. This study was designed to detect the CD virus through the RT-PCR technique and perform the analysis of the data collected to have a current view of the behavior of this virus in Lima, Peru. Whole blood samples from 52 unvaccinated canines with clinical signs compatible with canine distemper were collected between June 2012 and January 2015. The nucleoprotein of 287 bp was successfully amplified in 32.7% (17/52) of the samples analyzed. In addition, it was found a greater detection of the virus, but not significative, in individuals that manifested systemic clinical signs (respiratory and digestive signs vs nervous) and within the age range of 1.5-4 months.

引用

页码：964 / 971

页数：8

共 25 条

[1]

AMUDE A.M., 2006, CLIN VET, V60, P60

[2] Morbillivirus infections, with special emphasis on morbilliviruses of carnivores [J].

Barrett, T .

VETERINARY MICROBIOLOGY, 1999, 69 (1-2) :3-13

[3] Pathogenesis and immunopathology of systemic and nervous canine distemper [J].

Beineke, A. ;

Puff, C. ;

Seehusen, F. ;

Baumgaertner, W. .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2009, 127 (1-2) :1-18

[4]

Blancou Jean, 2004, Hist Med Vet, V29, P35

[5] Modulation of immune response during canine distemper virus infection: therapeutic and vaccine development implications [J].

Cespedes, P. F. ;

Cruz, P. ;

Navarro, C. O. .

ARCHIVOS DE MEDICINA VETERINARIA, 2010, 42 (02) :15-28

[6]

Craig E., 2000, ENFERMEDADES INFECCI

[7]

Deem SL, 2000, J ZOO WILDLIFE MED, V31, P441, DOI 10.1638/1042-7260(2000)031[0441:CDITCA]2.0.CO

[8]

[9]

Ettinger S, 1997, TRATADO MED INTERNA, P234

[10]

FENNER F, 1992, VIROLOGIA VET

← 1 2 3 →