The "Sympathetic" Kidney: Multiples Effects of Renal Sympathetic Nerve Ablation

被引：0

作者：

Seravalle, Gino ^{[1
]}

Grassi, Guido ^{[2
,3
]}

机构：

[1] S Luca Hosp, Cardiol Dept, IRCCS Ist Auxol Italiano, Milan, Italy

[2] Univ Milano Bicocca, Osped San Gerardo, Clin Med, Monza, Italy

[3] IRCCS Multimed, Milan, Italy

来源：

CURRENT HYPERTENSION REVIEWS | 2012年 / 8卷 / 04期

关键词：

Arterial hypertension; sympathetic nervous system; renal afferents; renal denervation;

D O I：

10.2174/1573402111208040250

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Sympathetic neural mechanisms are involved in the development and progression of hypertension. In the last few years the role of renal nerves as regulators of kidney function, volume homeostasis and blood pressure control and as potential target of therapeutic intervention has received renewed interest. Data obtained by the radiofrequency catheter-based procedure for renal denervation have provided evidence for a prolonged sympathoinhibitory and blood pressure lowering effect but also for a positive effect on metabolism and on target organ damage.

引用

页码：250 / 255

页数：6

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