INFLAMMATORY BRONCHIAL POLYPS ASSOCIATED WITH ASTHMA - RESOLUTION WITH INHALED CORTICOSTEROID

被引:21
作者
NIIMI, A
AMITANI, R
IKEDA, T
KUBO, Y
TANAKA, E
KUZE, F
机构
[1] Department Infection/Inflammation, Chest Disease Research Institute, Kyoto University, Shgoin, Sakyo-ku, Kyoto 606
关键词
ASTHMA; EOSINOPHILS; INFLAMMATORY BRONCHIAL POLYP; INHALED CORTICOSTEROID;
D O I
10.1183/09031936.95.08071237
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
In a 50 year old man who complained of cough and sputum, a small endobronchial tumour was found in the left main bronchus and was biopsied via bronchoscopy, The histological diagnosis was inflammatory polyp with marked infiltration of eosinophils. Six years later, the patient developed asthma At the same time, another polyp was found in the posterior basal bronchus of the right lower lobe, The appearance of the first polyp was unchanged endoscopically and histologically. Inhalation of beclomethasone dipropionate, 200 mu g b.i.d., was started, and symptoms of asthma soon subsided, In addition, the two polyps regressed and eventually disappeared after one year of treatment. Inhaled corticosteroids, being noninvasive and relatively safe, appear to be a possible therapeutic option in inflammatory bronchial polyps, especially in cases where the patient has asthma as an underlying condition, or the polyps are small and their management is not urgent.
引用
收藏
页码:1237 / 1239
页数:3
相关论文
共 12 条
[1]   ENDOBRONCHIAL POLYPOSIS SECONDARY TO THERMAL INHALATIONAL INJURY [J].
ADAMS, C ;
MOISAN, T ;
CHANDRASEKHAR, AJ ;
WARPEHA, R .
CHEST, 1979, 75 (05) :643-645
[2]   INFLAMMATORY BRONCHIAL POLYPS ASSOCIATED WITH ASTHMA [J].
ARGUELLES, M ;
BLANCO, I .
ARCHIVES OF INTERNAL MEDICINE, 1983, 143 (03) :570-571
[3]  
ASHLEY D J, 1963, Thorax, V18, P45, DOI 10.1136/thx.18.1.45
[4]   EFFICACY AND SAFETY OF INHALED CORTICOSTEROIDS IN ASTHMA - REPORT OF A WORKSHOP HELD IN EZE, FRANCE, OCTOBER 1992 [J].
BARNES, PJ ;
PEDERSEN, S .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 148 (04) :S1-S26
[5]   ENDOBRONCHIAL INFLAMMATORY POLYP ASSOCIATED WITH A FOREIGN-BODY - SUCCESSFUL TREATMENT WITH CORTICOSTEROIDS [J].
BERMAN, DE ;
WRIGHT, ES ;
EDSTROM, HW .
CHEST, 1984, 86 (03) :483-484
[6]  
GIBSON PG, 1989, LANCET, V1, P1346
[7]   RETAINED ENDOBRONCHIAL FOREIGN-BODY REMOVAL FACILITATED BY STEROID-THERAPY OF AN OBSTRUCTING, INFLAMMATORY POLYP [J].
MOISAN, TC .
CHEST, 1991, 100 (01) :270-270
[8]  
PARK T, 1984, AM REV RESPIR DIS, V130, P315
[9]   ENDOBRONCHIAL POLYP IN AN ASTHMATIC SUBJECT [J].
SHALE, DJ ;
LANE, DJ ;
FISHER, CWS ;
DUNNILL, MS .
THORAX, 1983, 38 (01) :75-76
[10]   ENDOBRONCHIAL POLYP AND CHRONIC SMOKE INJURY [J].
SMITH, RE .
POSTGRADUATE MEDICAL JOURNAL, 1989, 65 (768) :785-787